Analysis of ALA formation after infecting gerbils with various E. histolytica transfectants.

B2^p (A), A1^np (B) and B8^np transfectants (C) overexpressing various genes differentially expressed in clones A1^np and B2^p were used to intrahepatically infect mice. Seven days post infection, ALA formation was determined [area of ALA (mm²)]. Significance (p-values) was established by the Mann-Whitney U test. p-values were calculated relative to control (pNC transfectants of clone B2^p (A), A1^np (B) or B8^np (c), respectively). *p < 0.05, **p < 0.005, ***p < 0.001, **** p < 0.0001, ns: not significant. For detailed information see S1 Table.