Fig 1.TIF (291.14 kB)
Analysis of ALA formation after infecting gerbils with various E. histolytica clones.
figure
posted on 2016-08-30, 04:30 authored by Martin Meyer, Helena Fehling, Jenny Matthiesen, Stephan Lorenzen, Kathrin Schuldt, Hannah Bernin, Mareen Zaruba, Corinna Lender, Thomas Ernst, Harald Ittrich, Thomas Roeder, Egbert Tannich, Hannelore Lotter, Iris BruchhausCell lines HM-1:IMSS-A and HM-1:IMSS-B were cloned by a limited dilution method, resulting in 12 clones derived from HM-1:IMSS-A (A1–A12) and 12 clones derived from HM-1:IMSS-B (B1–B12). Gerbils were infected with 1 × 106 trophozoites of the different cell lines and clones. Seven days post infection, liver abscess formation was analysed and area of ALA (mm2) was determined. Significance (p-values) was established by the Mann-Whitney U test. p-values were calculated relative to control (HM-1:IMSS-A or HM-1:IMSS-B, respectively). *p = 0.0286, **p = 0.079. For detailed information see S1 Table.
