A new phenalenone derivative from the soil fungus Penicillium herquei PSU-RSPG93

Tansakul, Chittreeya; Rukachaisirikul, Vatcharin; Maha, Atip; Kongprapan, Thippaya; Phongpaichit, Souwalak; Hutadilok-Towatana, Nongporn; Borwornwiriyapan, Kawitsara; Sakayaroj, Jariya

doi:10.6084/m9.figshare.1122499.v7

gnpl_a_941363_sm0724.doc (664.5 kB)

A new phenalenone derivative from the soil fungus Penicillium herquei PSU-RSPG93

Version 7 2014-09-10, 07:02

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Version 5 2014-07-31, 15:10

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Version 2 2014-07-31, 11:43

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journal contribution

posted on 2014-09-10, 07:02 authored by Chittreeya Tansakul, Vatcharin Rukachaisirikul, Atip Maha, Thippaya Kongprapan, Souwalak Phongpaichit, Nongporn Hutadilok-Towatana, Kawitsara Borwornwiriyapan, Jariya Sakayaroj

One new phenalenone derivative, peniciherqueinone (1), together with five known phenalenone derivatives (2–6), one known anthraquinone (7) and two known acetophenones (8 and 9) were isolated from the soil fungus Penicillium herquei PSU-RSPG93. Their structures were established by spectroscopic evidence. The absolute configuration of 1 was determined by anisotropic effect and electronic circular dichroism spectroscopy. Compound 2 exhibited mild antioxidant activity and is noncytotoxic to Vero (African green monkey kidney fibroblasts) cell lines.