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Viannia MLSA network from Coughlan et al 2017

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modified on 20.07.2017, 16:21
Figure 1 from Coughlan et al 2017: Main: A neighbor-Net network of the concatenated sequences totalling 2,902 sites of four housekeeping genes for 102 Viannia based on uncorrected p-distances. The genes were glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGD), mannose phosphate isomerase (MPI) and isocitrate dehydrogenase (ICD). Black stars indicate isolates whose aneuploidy and copy number variants were examined. The L. guyanensis and L. naiffi genomes studied herein are highlighted in orange. Upper inset: The reference genomes of the L. braziliensis control is in the L. braziliensis complex (same node whose text is marked in red)as well as the also annotated L. peruviana PAB-4377 . Lower inset: L. guyanensis and L. naiffi complexes. Nodes with bold text represent samples examined for CNVs. The scale bar indicates the number of substitutions per site.

See also the MLSA diagram in Boité M C, Mauricio I L, Miles M A and Cupolillo E 2012 New insights on taxonomy, phylogeny and population genetics of Leishmania (Viannia) parasites based on multilocus sequence analysis. PLoS Negl. Trop. Dis. 6 e1888.