Dataset microbiota HPV y2020m09
datasetmodified on 02.10.2020, 20:29
Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru
Objective: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus.
Results: A total of 100 HPV-positive and 100 HPV- negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68% vs 32%), Actinobacteria (46% vs 33%), Fusobacterium (11% vs 6%) and Bacteroides (20% vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50% vs 33.33%), Bifidobacterium (50% vs 20.83%) and Enterococcus (50% vs 29.17%).
Keywords: Peru, HPV, Human papillomavirus, cervical cancer, microbiota, PCR