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Supplemental data for the manuscript: Efficacy and safety of weekly somatrogon vs daily somatropin in children with growth hormone deficiency: a phase 3 study

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modified on 2022-03-09, 14:34
This is supplemental data for this manuscript:


Supplemental Methods – This is a description of the additional inclusion and exclusion criteria and the adverse events of special interest.


Supplemental Table S1 – This dataset describes the incidence and severity of all-causality treatment-emergent adverse events.


Supplemental Table S2 – This dataset describes the treatment-related adverse events stratified according to whether subjects had two consecutive increases in IGF-1 SDS >2


Supplemental Table S3 – This dataset shows the values for glucose metabolism for subjects throughout the study.


Supplemental Figure S1 – This dataset shows the height velocities for all the individual subjects.


Supplemental Figure S2 – This dataset shows the instances of injection site pain for subjects throughout the study.


Funding

This study was sponsored by OPKO Health which is a co-development partner with Pfizer. Medical writing and editorial support was provided by Chu Kong Liew, PhD, CMPP, of Engage Scientific Solutions, and was funded by Pfizer.

Disclaimer

Somatrogon is not FDA approved for the indication in this publication