Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment and breast cancer survival

The data containing tumors from a cohort of racially diverse breast cancer patients residing in a designated health disparities catchment area of East North Carolina. By this analysis, staining intensity in the nucleus or cytoplasm of each cell in the annotated tumor regions is assigned one of fours scores: from negative staining (0), to weak staining (+1), moderate staining (2+) or strong staining (3+). The percent of cells in the annotated regions demonstrating one of the 4 different intensities are then aggregated to derive an H-score (H-score= 3 x [%3+] + 2 x [%2+] + 1 [%1+]), thus generating a continuous score from 0-300.