Dietary restriction transforms the mammalian protein sulfhydrome in a tissue-specific and cystathionine γ-lyase-dependent manner

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modified on 2020-12-16, 04:27

The Thermo Scientific™ Pierce™ Retention Time Calibration Mixture enables users of liquid chromatography (LC) and mass spectrometry (MS) to confirm correct operation of their LC and MS equipment. Applications of the calibration mixture include optimization of LC parameters, identification of total peptide elution window, and optimization of MS parameters. The calibration mixture can be used with the Thermo Scientific Pinpoint 1.1 software (www.thermoscientific.com/pinpoint) to predict peptide retention times based upon peptide sequence and ease the transfer of methods between LC and MS platforms. The equimolar calibration mixture contains 15 heavy isotope-labeled peptides with each peptide at 0.5pmol/µL (Product No. 88320) or 5pmol/µL (Product No. 88321).

Funding

This work was funded by NIH grants R00AG050777 and R01HL148352 to CH, an NIH shared instrument grant 1S10OD023436-01 to BW, an AFAR/Glenn Foundation Fellowship to YOH, and a Discovery Grant from the Natural Sciences and Engineering Research Council of Canada to RW.

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Aged Health Care

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Dietary restriction transforms the mammalian protein sulfhydrome in a tissue-specific and cystathionine γ-lyase-dependent manner

Funding

This work was funded by NIH grants R00AG050777 and R01HL148352 to CH, an NIH shared instrument grant 1S10OD023436-01 to BW, an AFAR/Glenn Foundation Fellowship to YOH, and a Discovery Grant from the Natural Sciences and Engineering Research Council of Canada to RW.

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