ZIKV EIP in Aedes aegypti
Published on by Olivia Winokur
To better understand the relationship between ZIKV EIPs and temperature, we evaluated the effect of adult mosquito exposure temperature on ZIKV infection, dissemination, and transmission in Ae. aegypti at four temperatures: 18°C, 21°C, 26°C, and 30°C. This is among the first studies to characterize the effects of temperature on ZIKV EIP in Ae. aegypti, and the first to do so based on feeding of mosquitoes on a live, viremic host. This information is critical for modeling ZIKV transmission dynamics to understand geographic and seasonal limits of ZIKV risk; it is especially relevant for determining risk in subtropical regions with established Ae. aegypti populations (e.g. California or Florida) as these regions typically experience cooler temperature ranges than tropical regions.
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Funding
National Aeronautics and Space Administration’s Applied Sciences Program in Health and Air Quality (Grant NNX15AF36G)
National Science Foundation Graduate Research Fellowship (Grant No. 1650042)
U.S. Centers for Disease Control and Prevention (Cooperative Agreement U01CK000516)
