|   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
| . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
E | G | S | L | L | V | G | T | S | R | G | R | I | V | V | A | D | V | S | P | Q | T | V | E | . |
. |
. |
. |
. |
. |
. |
D | S | D | G | E | L | Q | R | R | T | C | L | V | C | S | E | E | Q | T | P | V | G | D | I | V | V | P | P | . |
Query Conservation |   |
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   | . | . | . | . | . | . | . |   |
|   |
|   |
|   |   |   |   |
|
|
|   |
|   |
|
|   |   |
|   |
|
|
|   |   |
| . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
N | G | T | I | V | A | G | S | T | G | C | F | V | S | G | H | D | S | A | T | G | E | E | L | W | R | N | Y | F | I | P | R | A | R | W | M | T | G | A | W | G | Q | I | T | Y | D | P | V | T | N | L | V | H | Y | G | S | T | A | V | G |
Template Known Secondary structure |   |
T | T |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  | S | S |
|
|
|
|
|
|
| S |
|
| S |
|
|  |  |  | T | T | T | T |  |  |  |  |  |
|
|
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
S | K | H | A | V | S | T | L | V | R | C | V | R | S | N | A | A | V | C | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . |
|   |
|   |   |
|
|
|
|   |
|
|   |   |
|   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |
|   |
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | L | Y | G | T | N | T | R | F | A | V | R | P | D | T | G | E | I | V | W | R | H | Q | T | L | P | R | D | N | W | D | Q | E | C | T | F | E | M | M | V | T | N | V | D | V | Q | P | S | T | E | M | E | G | L | Q | S | I | N | P | N |
Template Known Secondary structure |   |
|
| T | T | S | S |  |  |  |  |  |
| T | T | T |
|
|  |  |  |  |  |  | S |
| S | S |
| S | S |
|
|
|
|
| S |
|
|  |  |  |  |  |  |  |
|
|
| T | T |
| T | T |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
251 | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 |
  |
  |   |
|
|
|
|
|
|
|
|
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
S | S | V | V | A | V | C | D | S | R | A | M | V | W | D | V | K | G | A | T | Q | P | V | H | T | W | V | P | S | V | D | S | S | K | N | S | P | N | E | Q | E | P | L | L | . |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|   |   |   |
|   |
|
|   |
|
|
|   |   |
|   | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | A | T | G | E | R | R | V | L | T | G | V | P | C | K | T | G | T | M | W | Q | F | D | A | E | T | G | E | F | L | W | A | R | D | T | N | Y | Q | N | M | I | E | S | I | D | E | N | G | I | V | T | V | N | E | D | A | I | E | Y | D |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |  |  |
|
| S | T | T |
|
|  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |
| S | S |
|
|
| S |  |  |  |  |
| T | T |
|
|  |  |  |
| T | T | T |
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
311 | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | A | Q | W | V | P | N | S | D | S | V | V | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | S | Y | S | G | S | L | V | F | T | D | I | R | T |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|
|
|
|
|
|
|
|
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|
Template Sequence |   |
V | C | P | T | F | L | G | G | R | D | W | P | S | A | A | L | N | P | D | S | G | I | Y | F | I | P | L | N | N | V | C | Y | D | M | M | N | T | S | N | V | T | K | L | P | P | G | K | D | M | I | G | R | I | D | A | I | D | I | S | T |
Template Known Secondary structure |   |
|
| S |
| T | T |
| S | S |
| S | S |
|
|  |  |  | T | T | T | T |  |  |  |  |  |  |  |
|
| B |
|
|
|
|
|
|
|
| S |
| B |
|
| T | T |
|
|
| S |  |  |  |  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
377 | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . |
  |
  |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | |
. | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Query Sequence |   |
K | E | G | S | T | S | K | L | S | L | P | A | R | R | G | C | M | A | R | C | A | D | F | N | T | L | L | P | F | A | L | A | T | A | S | S | D | G | I | I | S | V | F | D | C | R | Y | P | S | T | A | V | R | T | I | P | . |
S | L | H |
Query Conservation |   |
|
|   |   |
|
|
|
|   |
|
|   |
|
|   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |
|
|
|
|   | . |
|
|
|
Alig confidence |   |
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
|   | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|
|
|   |   | . |
|
|   |   |
|
|   |   |   |   |   |   |   |
Template Sequence |   |
G | R | . |
. |
. |
. |
. |
T | L | W | S | V | E | R | A | A | A | N | Y | S | P | V | L | S | T | . |
G | G | G | V | L | F | N | G | G | T | D | R | Y | F | R | A | L | S | Q | E | . |
T | G | E | T | L | W | Q | T | R | L | A | T | V |
Template Known Secondary structure |   |
|
| . | . | . | . | . |  |  |  |  |  |  |  | S | S |
|
|
|
|
|  |  |  |  | . | T | T | S |  |  |  |  |
| B | T | T | S |  |  |  |  |  |  | T | T | . | T |
|
|  |  |  |  |  |  |
| S | S |
|
Template Predicted Secondary structure |   |
|  | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  | . |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
449 | 450 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | |
. | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | |
. | 490 | . | . | . | . | . | . | . | . | . | 500 | . |
  |
  |   |
316 | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | |
|
|
. | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | D | I | M | S | L | K | Y | L | K | L | H | S | D | I | . |
. |
. |
I | A | T | G | G | V | D | G | S | V | V | L | W | N | L | R | S | L | P | T | Y | R | V | G | R | A | Q | Y | K | C | P | V | F | D | L |
Query Conservation |   |
|   |
|   |
|
|
|
|
|
|   |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |
|
|   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|   |   |   |   | . |
|
|   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
A | S | G | Q | A | I | S | Y | E | V | . |
D | G | M | Q | Y | V | A | I | A | G | G | G | V | S | Y | G | S | G | L | N | S | A | L | A | G | E | R | V | D | S | T | A | I | G | N | A | V | Y | V | F | A | L |
Template Known Secondary structure |   |
B |
| S |
|
|  |  |  |  |  | . | T | T |  |  |  |  |  |  |  |  |
| S |
|
| G | G | G | G | G | G | G | G |
| S | S |
|
|
|
|
|
|
| S |
|
|  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
502 | . | . | . | . | . | . | . | 510 | . | |
. | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . |
  |