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Job DescriptionNg99_____
Confidence100.00%DateTue Mar 12 12:31:53 GMT 2019
Rank3Aligned Residues391
% Identity14%Templatec5juyB_
PDB info PDB header:apoptosisChain: B: PDB Molecule:apoptotic protease-activating factor 1; PDBTitle: active human apoptosome with procaspase-9
Resolution4.10 Å
Model Dimensions (Å)X:88.853 Y:59.268 Z:57.097

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20..... ....30.........40.........50.........60
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Query Sequence  GFNSSQNNFKLPSSHLVGNVKVAD. KSWRNARSLSGLHDGGQNVTKSLLRSDITIEDSSC
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Template Sequence  HACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDK
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   620.........630.........640.........650.........660.........670.........
 
   61..... ...70.........80.........90... ......100.........110........
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Query Sequence  ICVNNQ. QNYIVQAGVGGRFQTIKVIQKSRSDAK. QFTNTTTVLDKKDSPIPNTNIFSPQ
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Template Sequence  KVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNT.
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   680.........690.........700.........710.........720.........730........
 
   119120.........130.........140.........150.........160....
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Query Sequence  FSGKFPGPIHCMDMLNQYLLIGSSNGECYVKTMDVASEKNNCLLDD. . . . . . . . . . . . . .
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Template Sequence  . MFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNEDMEVIVK
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   739740.........750.........760.........770.........780.........790.......
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  CCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQY
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   803......810.........820.........830.........840.........850.........860..
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  CVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVML
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   863......870.........880.........890.........900.........910.........920..
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  KQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDEN
Template Known Secondary structure  TTSSSS
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   923......930.........940.........950.........960.........970.........980..
 
   165....170.........180.........190.... ....
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Query Sequence  . . . . . . . . . . . . . . . . . . . SPNSIVKCQTFSHSKLKKSDQSSILTTPSP. . . . . . . EQYT
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Template Conservation                         
  
  
 
   
 
   

 
 


           
Template Sequence  GAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRG
Template Known Secondary structure  SSSS
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   983......990.........1000.........1010.........1020.........1030.........1040..
 
   199200.........210.........220.........230.........240.........250........
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Query Sequence  FSTKINNVQIERSENPKNFHTLENNRLHIWSFEKDDAPIQTIQGSRSPLWCSSWSSFNSN
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Template Sequence  HQETVKDFRLLKN. SR. LLSWSFDGTVKVWNIITGNK. EKDFVCHQGTVLSCDISH. DAT
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SS.S
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   1043......1050..... .. ..1060.........1070....... ..1080.........1090..... ...
 
   259260.........270.........280.........290.........300.........310........
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Query Sequence  LILIGGVSKAVKLIDTRSMGIANANIQFSHCDAITDVQWSPLLPYWFASCSTDGLIYVWD
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Template Sequence  KFSSTSADKTAKIWSFDLLLPLHE. . LRGHNGCVRCSAFSV. DSTLLATGDDNGEIRIWN
Template Known Secondary structure  SS
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   10991100.........1110.........1120.. .......1130....... ..1140.........1150.....
 
   319320.........330 .........340.........350.........360.........370
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Query Sequence  QRYAAEPIKILE. . . . . . . . GHNNVVKKISWSRSHVEVLASGGVDHSVKLWSLRTEPHHV
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Template Sequence  VSNG. ELLHLCAPLSEEGAATHGGWVTDLCFSP. DGKMLISAG. . GYIKWWNVVTGESSQ
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   1156... 1160.........1170.........1180....... ..1190...... ...1200.........1210.
 
   371........380.........390.........400.........410
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Query Sequence  LTTLDKGFFSDSILGLSFSNVTPNQLFANSASGELLAISV
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Template Sequence  . . . . TFYTNGTNLKKIHVSP. DFKTYVTVDNLGILYILQT
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   1212.......1220....... ..1230.........1240......
 
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Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
 
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Lawrence Kelley, Michael Sternberg 
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