|   |
101 | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
. | . | . | |
|
|
|
|
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . |  |  |  | . | . | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | S | T | E | P | L | S | S | V | E | W | C | E | G | . |
. |
S | L | L | . |
. |
. |
. |
. |
V | G | T | S | R | G | R | I | V | V | A | D | V | S | P | Q | T | V | E | D | S | D | G | E | L | Q | R | R | T | C | L | V | C | S | E | E |
Query Conservation |   |
|
|
|
|   |
|
|
|
|
|
|
|
|
| . | . |   |
|
| . | . | . | . | . |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |
|   |
|   |   |   |   |
|
|
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |
|
|   |
|
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
Template Sequence |   |
D | G | T | V | A | L | R | G | Y | A | F | S | E | D | G | E | Y | F | A | Y | G | L | S | A | S | G | S | D | W | V | T | I | K | F | M | K | V | D | G | A | K | E | L | P | . |
D | V | L | E | R | V | K | F | S | M | A | W | T | H | D |
Template Known Secondary structure |   |
S | S |
|  |  |  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |  |  | T | T | T | T |  |  |  |  | . |  |  |  |  |  |  |
|
|
|
|  |  |
| T | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
  |
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | T | P | V | G | D | I | V | V | P | P | S | K | H | A | V | S | T | L | V | R | C | V | R | S | N | A | A | V | C | S | S | S | V | V | A | V | C | D | S | R | A | M | V | W | D | V | K | G | A | T | Q | P | V | H | T | W | V | P | S |
Query Conservation |   |
|   |   |
|   |
|
|
|   |   |
|
|   |
|   |   |
|
|
|
|   |
|
|   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
G | K | G | M | F | Y | N | A | Y | P | Q | Q | D | G | K | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | G | T | E | T | S | T | N | L | H | Q | K | L | Y | Y | H | V | L | G | T | D | . |
. |
. |
. |
. |
. |
. |
Q | S | E |
Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |
|
|
|
| S | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | S | S | S |
|
|
|
|
|
|
|
|  |  |  |  |  |  | T | T | S |
| . | . | . | . | . | . | . | G | G | G |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
182 | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 220 | . |
  |
  |   |
214 | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
Query Sequence |   |
V | D | S | S | K | N | S | P | N | E | Q | E | P | L | L | F | A | Q | W | V | P | N | S | D | S | V | V | L | . |
T | G | S | Y | S | G | S | L | V | F | T | D | I | R | T | K | E | G | S | T | S | K | L | S | L | . |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |
|   |
|
|   |
|
|
|   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|   |
| . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | I | L | C | A | E | F | P | D | E | P | K | W | M | G | G | A | E | L | S | D | D | G | R | Y | V | L | L | S | I | R | E | G | D | P | V | N | R | L | W | Y | C | D | L | Q | Q | E | S | N | G | I | T | G | I | L | K | W | V | K | L |
Template Known Secondary structure |   |
|  |  |  |  |
|
| T | T |
| T | T |
|  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | G | G | G | S | S | S | S | S |
| S | S |
|
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
267 | . | . | 270 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | A | R | R | G | C | M | A | R | C | A | D |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|   |   |   |
|   |
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
I | D | N | F | E | G | E | Y | D | Y | V | T | N | E | G | T | V | F | T | F | K | T | N | R | H | S | P | N | Y | R | L | I | N | I | D | F | T | D | P | E | E | S | K | W | K | V | L | V | P | E | H | E | K | D | V | L | E | W | V | A |
Template Known Secondary structure |   |
 |
| S | S | S | S |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
| T | T |
| T | T |
|  |  |  |  |  |  | T | T | B |
|
| G | G | G |
|  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
283 | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . |
  |
  |   |
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | |
|
. | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | |
|
|
|
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
F | N | T | L | L | P | F | A | L | A | T | A | S | S | D | G | . |
. |
I | I | S | V | F | D | C | R | Y | P | S | T | A | V | R | T | I | P | S | L | H | G | D | I | M | S | L | K | Y | L | K | L | H | S | D | I | I | A | . |
. |
. |
. |
Query Conservation |   |
|
|
|   |
|
|   |
|
|
|
|
|
|   |
|
| . | . |
|
|
|
|
|
|
|
|   |
|   |
|   |
|
|
|
|   |
|
|
|
|   |
|   |
|
|
|
|
|
|   |
|
|
|
|
|
| . | . | . | . |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |   | . |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
C | V | R | . |
S | N | F | L | V | L | C | Y | L | H | D | V | K | N | T | L | Q | L | H | D | L | A | . |
T | G | A | L | L | K | I | F | P | L | E | V | G | S | V | V | G | Y | S | G | Q | K | . |
K | D | T | E | I | F | Y | Q | F | T |
Template Known Secondary structure |   |
 |  | T | . | T | T |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | . | T |
|
|  |  |  |  |  |
|
|
| S | S |  |  |  |  |  |  |
|
| T | . | T |
| S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
| . |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
343 | . | . | |
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | |
. | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | |
390 | . | . | . | . | . | . | . | . | . |
  |
  |   |
333 | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | G | G | V | D | G | S | V | V | L | W | N | L | R | S | L | P | T | Y | R | V | G | R | A | Q | Y | K | C | P | V | F | D | L |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |
|
|   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |
|   |
Template Sequence |   |
S | F | L | S | P | G | I | I | Y | H | C | D | L | T | K | E | E | L | . |
. |
E | P | R | V | F | R | E | V | T | V | K | G | I |
Template Known Secondary structure |   |
| S | S |
|
|
|  |  |  |  |  |  | T | T | S | S | S |
| . | . |
|
|  |  |  |  |  |
|
|
| T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | |
|
. | . | 420 | . | . | . | . | . | . | . | . | . | 430 |
  |