Return to main results Retrieve Phyre Job Id

Job Descriptionexo99____
Confidence99.94%DateMon Feb 25 17:28:45 GMT 2019
Rank92Aligned Residues274
% Identity14%Templatec5mqfE_
PDB info PDB header:splicingChain: E: PDB Molecule:pre-mrna-processing factor 17; PDBTitle: cryo-em structure of a human spliceosome activated for step 2 of2 splicing (c* complex)
Resolution5.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   66...70.........80.........90.........100.........110... . .....120..
Predicted Secondary structure 
































.
..

Query SS confidence 















































.
. .







Query Sequence  GLNPLSTSGACVGLLTMESAEAKLSGMSKMQWLNLPSTEPLSSVEWCE. G. . SLLVGTSR
Query Conservation   
  

 

  
 


 



  



 
 








 







.
.. 




 
Alig confidence 



















..

























.
..







Template Conservation   
  
 




  


   
..           
 

   
  
  

 

  
 
 
 
Template Sequence  HINDFMFEQQRRTFATYGYA. . KCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMD
Template Known Secondary structure 
TT




..






SS

SS

TTTSSTT
Template Predicted Secondary structure 







..













Template SS confidence 



























































   119120.........130........ .140.........150.........160.........170......
 
   123......130...... ...140.........150.........160.........170.........180
Predicted Secondary structure 







..




































Query SS confidence 













. .











































Query Sequence  GRIVVADVSPQTVE. . DSDGELQRRTCLVCSEEQTPVGDIVVPPSKHAVSTLVRCVRSNA
Query Conservation 









 

 .. 
 
 
    


 
 

  
 


  

 
  



 

  
 
Alig confidence 













..











































Template Conservation    
 

                                                      
Template Sequence  CKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRF
Template Known Secondary structure  S

SSS






SS

SSSSTTT
B
TTSS

B

Template Predicted Secondary structure 




















































Template SS confidence 



























































   311........320.........330.........340.........350.........360.........370
 
   181........190..... ....200.........210.........220.........230......
Predicted Secondary structure 








....

























Query SS confidence 














. . . .








































Query Sequence  AVCSSSVVAVCDSRA. . . . MVWDVKGATQPVHTWVPSVDSSKNSPNEQEPLLFAQWVPNS
Query Conservation    









 

....








 

  
  
   
 

 


  
 







Alig confidence 














....








































Template Conservation                                                              
Template Sequence  TNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDEN
Template Known Secondary structure 

SS



SSS


TTS

TTSS


S
SS

TTS
Template Predicted Secondary structure 























































Template SS confidence 



























































   371........380.........390.........400.........410.........420.........430
 
   237..240.........250.........260......
Predicted Secondary structure 

















..............................
Query SS confidence 





























. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  DSVVLTGSYSGSLVFTDIRTKEGSTSKLSL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation 







 












  



 
..............................
Alig confidence 
.



























..............................
Template Conservation   .                                                          
Template Sequence  R. RFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFG
Template Known Secondary structure  S.
TTS


SSSS


TTSS
S
S




TTSSTTT
Template Predicted Secondary structure 
.























































Template SS confidence 



























































   431 ........440.........450.........460.........470.........480.........
 
   267..270.........280.........290.........300.........310..
Predicted Secondary structure  ..............





















Query SS confidence  . . . . . . . . . . . . . .













































Query Sequence  . . . . . . . . . . . . . . PARRGCMARCADFNTLLPFALATASSDGIISVFDCRYPSTAVRTIP
Query Conservation  ..............
 

   
 





 

 





 









 
 
 



 
Alig confidence  ..............














.



















.








Template Conservation                             
 .    
 


 

 
 


  .       
 
Template Sequence  AQNRFRLNKKKIFKGHMVAGYACQVDFSP. DMSYVISGDGNGKLNIWDWK. TTKLYSRFK
Template Known Secondary structure 
SSSSS









SS

BT.TTT
TTS

T.TSS


Template Predicted Secondary structure 



















.







.

Template SS confidence 



























































   490.........500.........510........ .520.........530........ .540.......
 
   313......320.........330.........340....
Predicted Secondary structure 















Query SS confidence 































Query Sequence  SLHGDIMSLKYLKLHSDIIATGGVDGSVVLWN
Query Conservation 



 
 





 

















Alig confidence 































Template Conservation   
   
  
  

     
 
 
 

 
 


Template Sequence  AHDKVCIGAVWHPHETSKVITCGWDGLIKLWD
Template Known Secondary structure 

SS




SSSS

B
SS
B
Template Predicted Secondary structure 















Template SS confidence 































   548.550.........560.........570.........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Michael Sternberg 
Disclaimer
Terms and Conditions

Phyre2 is part of Genome3D