Proteins in the SNF2 Family
(as of July 1995 - see Eisen et al)

Protein	Size (aa)	Species	Proposed Subfamily	Possible Function/Comments	References
SNF2	1703	S.cerevisiae	SNF2	Transcription activation. DNA-dependent ATPase. Alters chromatin structure?	1, 2, 3
STH1	1359	S.cerevisiae	SNF2	Cell cycle control. Required for normal growth.	1, 2
BRM	1638	D.melanogaster	SNF2	Transcription activation of homeotic genes.	1, 2, 3
BRG1	1022	Mouse	SNF2	Binds retinoblastoma protein.	1
BRG1	1613	Human	SNF2	Transcription coactivation with hormone receptors.	1, 2
hBRM	1586	Human	SNF2	Transcription coactivation with hormone receptors.	1, 2, 3
SNF2L	976	Human	SNF2L	?	1
ISWI	1027	D.melanogaster	SNF2L	?	1
F37A4.8	971	C.elegans	SNF2L	?	1
YB95	1143	S.cerevisiae	SNF2L	?	1
CHD-1	940	Mouse	CHD1	Binds DNA.	1
SYGP4	1468	S.cerevisiae	CHD1	?
ETL-1	1136	Mouse	ETL1	Expressed very early in development. Concentrated in CNS and epithelium.	1
FUN30	1131	S.cerevisiae	ETL1	Mutants have increased UV resistance.
MOT1	1867	S.cerevisiae	MOT1	Transcription repression. Removes TBP from DNA. DNA-dependent ATPase.	1
RAD26	1085	S.cerevisiae	ERCC6	Transcription-coupled repair.	1, 2
ERCC6	1493	Human	ERCC6	Transcription-coupled repair. Defective in Cockayne's syndrome group B.	1, 2
RAD54	898	S.cerevisiae	RAD54	Recombination repair.	1
DNRPPX	852	S.pombe	RAD54	?
YBS3	958	S.cerevisiae	RAD54	?
NUCPRO	1298	Human	RAD54	Defective in X-linked mental retardation/alpha-thalassemia	1
NUCPRO	996	Mouse	RAD54	?
RAD16	790	S.cerevisiae	RAD16	Nucleotide excision repair of silent genes.	1, 2, 3
RAD5	1169	S.cerevisiae	RAD16	Post-replication repair. GT repeats more stable in mutants.	1, 2
RAD8	1133	S.pombe	RAD16	Mutants have increased sensitivity to UV and gamma irradiation.	1
HIP116A	1009	Human	RAD16	DNA-dependent ATPase. Binds HIV and SPH motifs of SV40 enhancer.	1
NPHCG42	506	A. californica	none	Viral encoded protein.
lodestar	1061	D.melanogaster	none	Mutants have excessive chromosome breakage and tangling in mitosis.	1
HepA	968	E.coli	none	Induced by DNA damage.