Characteristics of Proposed Subfamilies

Sub-family Members of Subfamily Known Motifs in All Bootstrap Values
(PPars, Fitch, NJ)
Conserved Function
SNF2 hBRM-human
BRG1-human
BRG1-mouse
BRM-Dmelano
STH1-yeast
SNF2-yeast
bromodomain 100,100,100 Transcription activation.
Remove histones from DNA
SNF2L SNF2L-human
F37A4-Celegans
ISWI-Dmelano
YB95-yeast
none 100,100,100 Nucleosome remodelling?
CHD1 CHD1-mouse
SYGP4-yeast
chromodomain 100,100,100 ?
ETL1 ETL1-mouse
FUN30-yeast
none 97,100,100 ?
ERCC6 ERCC6-human
RAD26-yeast
none 100,100,100 Transcription-coupled repair.
Moves stalled RNA polymerase?
RAD16 RAD16-yeast
RAD5-yeast
RAD8-pombe
HIP116A-human
RING finger 47,83,62 ?
RAD54 RAD54-yeast
YB53-yeast
DNRPPX-pombe
NUCPRO-human
NUCPRO-mouse
none 81,92,94 Recombination repair.
MOT1 MOT1-yeast none n/a,n/a,n/a Removes TATA-binding protein from DNA.