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A Novel Chiral Pentamine Ligand for Enantioselective α-Alkylation of Acyclic Lithium Amide Enolates. Optimization of Chiral Ligands for Asymmetric Reactions Using Solid-Phase Organic Synthesis

Posted on 1999-06-06 - 00:00
A novel pentamine ligand has been developed for enantioselective α-alkylation of simple acyclic lithium amide enolates. It has been demonstrated that solid-phase organic synthesis provides a powerful and rapid method for finding efficient chiral ligands.

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