Development of the Intramolecular Prins Cyclization/Schmidt Reaction for the Construction of the Azaspiro[4,4]nonane: Application to the Formal Synthesis of (±)-Stemonamine

Zhang, Fu-Min

Development of the Intramolecular Prins Cyclization/Schmidt Reaction for the Construction of the Azaspiro[4,4]nonane: Application to the Formal Synthesis of (±)-Stemonamine

Posted on 2011-02-18 - 00:00

A TiCl₄-promoted tandem intramolecular Prins cyclization/Schmidt reaction has been designed and developed to be an efficient method for the construction of the azaspiro[4,4]nonane. The present tandem protocol has been employed to construct the tricyclic azaquaternary skeleton (ring A, B, and C) of stemonamine.

CITE THIS COLLECTION

Chen, Zhi-Hua; Tu, Yong-Qiang; Zhang, Shu-Yu; Zhang, Fu-Min (2016). Development of the Intramolecular Prins Cyclization/Schmidt Reaction for the Construction of the Azaspiro[4,4]nonane: Application to the Formal Synthesis of (±)-Stemonamine. ACS Publications. Collection. https://doi.org/10.1021/ol102955e

https://doi.org/10.1021/ol102955e

or

Select your citation style and then place your mouse over the citation text to select it.