Supplementary material from "Dietary restriction increases variability in longevity"

Published on 2017-02-28T09:19:30Z (GMT) by
Nutritional environments, particularly those experienced during early life, are hypothesized to affect longevity. A recent cross-taxa meta-analysis found that, depending upon circumstance, average longevity may be increased or decreased by early-life dietary restriction. Unstudied are the effects of diet during development on among-individual variance in longevity. Here, we address this issue using emerging methods for meta-analysis of variance. We found that, in general, standard deviation (s.d.) in longevity is around 8% higher under early-life dietary restriction than a standard diet. The effects became especially profound when dietary insults were experienced prenatally (s.d. increased by 29%) and/or extended in to adulthood (s.d. increased by 36.6%). Early-life dietary restriction may generate variance in longevity as a result of increased variance in resource acquisition or allocation, but the mechanisms underlying these largely overlooked patterns clearly warrant elucidation.

Cite this collection

Senior, A. M.; Nakagawa, S.; Raubenheimer, D.; Simpson, S. J.; Noble, D. W. A. (2017): Supplementary material from "Dietary restriction increases variability in longevity". figshare.

Retrieved: 05:21, Sep 22, 2017 (GMT)