Stereoselective Rh-Catalyzed Hydrogenative Desymmetrization
of Achiral Substituted 1,4-Dienes
Version 2 2016-06-13, 16:25
Version 1 2016-05-26, 20:48
Posted on 2016-05-27 - 00:00
Highly
efficient catalytic stereoselective hydrogenative desymmetrization
reactions mediated by rhodium complexes derived from enantiopure phosphine–phosphite
(P–OP) ligands are described. The highest performing ligand,
which contains a TADDOL-derived phosphite fragment [TADDOL = (2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)],
presented excellent catalytic properties for the desymmetrization
of a set of achiral 1,4-dienes, providing access to the selective
formation of a variety of enantioenriched secondary and tertiary alcohols
(six examples, up to 92% ee).
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Fernández-Pérez, Héctor; Lao, Joan R.; Vidal-Ferran, Anton (2016). Stereoselective Rh-Catalyzed Hydrogenative Desymmetrization
of Achiral Substituted 1,4-Dienes. ACS Publications. Collection. https://doi.org/10.1021/acs.orglett.6b01088
or
Select your citation style and then place your mouse over the citation text to select it.
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (3)
HF
Héctor Fernández-Pérez
JL
Joan R. Lao
AV
Anton Vidal-Ferran