Spectroscopic photoacoustic imaging of radiofrequency ablation in the left atrium
Posted on 2018-02-23 - 17:31
Catheter-based radiofrequency ablation for atrial fibrillation has long-term success in 60-70% of cases. A better assessment of lesion quality, depth, and continuity could improve the procedure’s outcome. We investigate here photoacoustic contrast between ablated and healthy atrial-wall tissue in vitro in wavelengths spanning from 410 nm to 1000 nm. We studied single- and multi-wavelength imaging of ablation lesions and we demonstrate that a two-wavelength technique yields precise detection and delineation of lesions, achieving a diagnostic accuracy of 97%. We compare this with a best single-wavelength (640 nm) analysis that correctly identifies 82% of lesions. We discuss the origin of relevant spectroscopic features and perspectives for translation to clinical imaging.
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Iskander-Rizk, Sophinese; Kruizinga, Pieter; van der Steen, Ton; van Soest, Gijs (2018). Spectroscopic photoacoustic imaging of radiofrequency ablation in the left atrium. Optica Publishing Group. Collection. https://doi.org/10.6084/m9.figshare.c.3911866.v1
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AUTHORS (4)
SI
Sophinese Iskander-Rizk
PK
Pieter Kruizinga
Tv
Ton van der Steen
Gv
Gijs van Soest