Ruthenium-Catalyzed Cycloisomerization of 2‑Alkynylanilides: Synthesis of 3‑Substituted Indoles by 1,2-Carbon Migration

Published on 2017-06-19T04:29:44Z (GMT) by
We developed ruthenium-catalyzed cycloisomerization of alkynylanilides that gave 3-substituted indoles in high yields. The reaction proceeded via the disubstituted vinylidene ruthenium complex that was formed by the 1,2-carbon migration.

Cite this collection

Watanabe, Takuma; Mutoh, Yuichiro; Saito, Shinichi (2017): Ruthenium-Catalyzed

Cycloisomerization of 2‑Alkynylanilides:

Synthesis of 3‑Substituted Indoles by 1,2-Carbon Migration. ACS Publications.

https://doi.org/10.1021/jacs.7b04564

Retrieved: 19:06, Jun 23, 2017 (GMT)