Palladium-Catalyzed Oxidative
Aryltrifluoromethylation of Activated Alkenes at Room Temperature

Liu, Guosheng

Palladium-Catalyzed Oxidative Aryltrifluoromethylation of Activated Alkenes at Room Temperature

Posted on 2012-01-18 - 00:00

A palladium-catalyzed intramolecular oxidative aryltrifluoromethylation reaction of activated alkenes has been explored. The reaction allows for an efficient synthesis of a variety of CF₃-containing oxindoles. Preliminary mechanistic study indicated that the reaction involves a C_sp³–Pd^IV(CF₃) intermediate, which undergoes reductive elimination to afford a C_sp³–CF₃ bond.

CITE THIS COLLECTION

Mu, Xin; Wu, Tao; Wang, Hao-yang; Guo, Yin-long; Liu, Guosheng (2016). Palladium-Catalyzed Oxidative Aryltrifluoromethylation of Activated Alkenes at Room Temperature. ACS Publications. Collection. https://doi.org/10.1021/ja210614y

https://doi.org/10.1021/ja210614y

or

Select your citation style and then place your mouse over the citation text to select it.