Microbial transformation of the anti-diabetic agent corosolic acid by Cunninghamella echinulata

Chu, Zhi-Yong

Microbial transformation of the anti-diabetic agent corosolic acid by Cunninghamella echinulata

Posted on 2016-05-30 - 17:12

The pentacyclic triterpenoid corosolic acid was metabolized by Cunninghamella echinulata CGMCC 3.2000 to its C-24 aldehyde group metabolite and five other hydroxylated metabolites: madasiatic acid (2), 2α, 3β, 7β-trihydroxyurs-12-en-28-oic acid (3), 2α, 3β, 15α-trihydroxyurs-12-en-28-oic acid (4), 2α, 3β, 6β, 7β-tetrahydroxyurs-12-en-28-oic acid (5), 2α, 3β, 7β, 15α-tetrahydroxyurs-12-en-28-oic acid (6), and 2α, 3β,7β-trihydroxy-24-al-urs-12-en-28-oic acid (7); compounds 3, 5, and 7 were new compounds. The α-glucosidase inhibitory effects of the metabolites were also evaluated.

CITE THIS COLLECTION

DataCite

3 Biotech

3D Printing in Medicine

3D Research

3D-Printed Materials and Systems

4OR

AAPG Bulletin

AAPS Open

AAPS PharmSciTech

Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg

ABI Technik (German)

Academic Medicine

Academic Pediatrics

Academic Psychiatry

Academic Questions

Academy of Management Discoveries

Academy of Management Journal

Academy of Management Learning and Education

Academy of Management Perspectives

Academy of Management Proceedings

Academy of Management Review

Microbial transformation of the anti-diabetic agent corosolic acid by Cunninghamella echinulata. Taylor & Francis. Feng, Xu; Lu, Yan-Hua; Liu, Zhen; Li, Dai-Ping; Zou, Ying-Xin; Fang, Yi-Qun; et al..

https://doi.org/10.6084/m9.figshare.c.3262201.v1

or

Select your citation style and then place your mouse over the citation text to select it.