Generation of Aza-ortho-xylylenes via
Ring Opening of
2-(2-Acylaminophenyl)aziridines:
Application in the Construction of the
Communesin Ring System
Posted on 2006-08-31 - 00:00
A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl)aziridines is
described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.
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Crawley, Seth L.; Funk, Raymond L. (2016). Generation of Aza-ortho-xylylenes via
Ring Opening of
2-(2-Acylaminophenyl)aziridines:
Application in the Construction of the
Communesin Ring System. ACS Publications. Collection. https://doi.org/10.1021/ol061461d
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