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Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1N‑(6-Methylpyridyl-2-methyl) Protecting Group

Posted on 2022-05-17 - 00:04
6-Methylpyridyl-2-methyl protected tetrazoles can be C–H deprotonated using the turbo-Grignard reagent and involved in the reactions with aldehydes and ketones. The protecting group can be cleaved under reductive electrochemical conditions using Pb bronze as a cathode and Zn as a sacrificial anode.

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