Functionalization of Tetrazoles Bearing the Electrochemically
Cleavable 1N‑(6-Methylpyridyl-2-methyl) Protecting
Group
Posted on 2022-05-17 - 00:04
6-Methylpyridyl-2-methyl
protected tetrazoles can be C–H
deprotonated using the turbo-Grignard reagent and involved in the
reactions with aldehydes and ketones. The protecting group can be
cleaved under reductive electrochemical conditions using Pb bronze
as a cathode and Zn as a sacrificial anode.