Data from: Large and fast human pyramidal neurons associate with intelligence

Posted on 20.12.2018 - 03:31
It is generally assumed that human intelligence relies on efficient processing by neurons in our brain. Although gray matter thickness and activity of temporal and frontal cortical areas correlate with IQ scores, no direct evidence exists that links structural and physiological properties of neurons to human intelligence. Here, we find that high IQ scores and large temporal cortical thickness associate with larger, more complex dendrites of human pyramidal neurons. We show in silico that larger dendritic trees enable pyramidal neurons to track activity of synaptic inputs with higher temporal precision, due to fast action potential kinetics. Indeed, we find that human pyramidal neurons of individuals with higher IQ scores sustain fast action potential kinetics during repeated firing. These findings provide the first evidence that human intelligence is associated with neuronal complexity, action potential kinetics and efficient information transfer from input s to output within cortical neurons.

CITE THIS COLLECTION

Goriounova, Natalia A; Heyer, Djai B; Wilbers, René; Verhoog, Matthijs B; Giugliano, Michele; Verbist, Christophe; et al. (2018): Data from: Large and fast human pyramidal neurons associate with intelligence. Dryad. Collection. https://doi.org/10.5061/dryad.83dv5j7
or
Select your citation style and then place your mouse over the citation text to select it.

dc.identifier.uri

http://hdl.handle.net/10255/dryad.192069

prism.publicationName

eLife

SHARE

email

Usage metrics

Mirror of Dryad

AUTHORS (16)

Natalia A Goriounova
Djai B Heyer
René Wilbers
Matthijs B Verhoog
Michele Giugliano
Christophe Verbist
Joshua Obermayer
Amber Kerkhofs
Harriët Smeding
Maaike Verberne
Sander Idema
Johannes C Baayen
Anton W Pieneman
Christiaan PJ de Kock
Martin Klein
Huibert D Mansvelder
need help?