Cobalt(III) Porphyrin Catalyzed Aza-Diels–Alder Reaction

Matsubara, Seijiro

Cobalt(III) Porphyrin Catalyzed Aza-Diels–Alder Reaction

Posted on 2012-09-21 - 00:00

An efficient protocol for the aza-Diels–Alder reaction of electron-deficient 1,3-dienes with unactivated imines in the presence of a cationic cobalt(III) porphyrin complex was developed. The transformation proceeded smoothly to afford the desired piperidine scaffold within 2 h at ambient temperature. Highly chemoselective cycloaddition of imines with dienes in the presence of a variety of carbonyl compounds was also demonstrated.

CITE THIS COLLECTION

Wakabayashi, Ryota; Kurahashi, Takuya; Matsubara, Seijiro (2016). Cobalt(III) Porphyrin Catalyzed Aza-Diels–Alder Reaction. ACS Publications. Collection. https://doi.org/10.1021/ol3020946

https://doi.org/10.1021/ol3020946

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