Catalytic Hydrothiolation: Regio- and Enantioselective Coupling of Thiols and Dienes

Published on 2018-08-09T18:49:29Z (GMT) by
We report a Rh-catalyzed hydrothiolation of 1,3-dienes, including petroleum feedstocks. Either secondary or tertiary allylic sulfides can be generated from the selective addition of a thiol to the more substituted double bond of a diene. The catalyst tolerates a wide range of functional groups, and the loading can be as low as 0.1 mol %.

Cite this collection

Yang, Xiao-Hui; Davison, Ryan T.; Dong, Vy M. (2018): Catalytic

Hydrothiolation: Regio- and Enantioselective

Coupling of Thiols and Dienes. ACS Publications. Collection.