Biodegradable π‑Conjugated Oligomer Nanoparticles
with High Photothermal Conversion Efficiency for Cancer Theranostics
Posted on 2019-11-08 - 22:43
We
developed a biodegradable photothermal therapeutic (PTT) agent,
π-conjugated oligomer nanoparticles (F8-PEG NPs), for highly
efficient cancer theranostics. By exploiting an oligomer with excellent
near-infrared (NIR) absorption, the nanoparticles show a high photothermal
conversion efficiency (PCE) up to 82%, surpassing those of reported
inorganic and organic PTT agents. In addition, the oligomer nanoparticles
show excellent photostability and good biodegradability. The F8-PEG
NPs are also demonstrated to have excellent biosafety and PTT efficacy
both in vitro and in vivo. This
contribution not only proposes a promising oligomer-based PTT agent
but also provides insight into developing highly efficient nanomaterials
for cancer theranostics.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Li, Xiaozhen; Liu, Lu; Li, Shengliang; Wan, Yingpeng; Chen, Jia-Xiong; Tian, Shuang; et al. (2019). Biodegradable π‑Conjugated Oligomer Nanoparticles
with High Photothermal Conversion Efficiency for Cancer Theranostics. ACS Publications. Collection. https://doi.org/10.1021/acsnano.9b05383
or
Select your citation style and then place your mouse over the citation text to select it.
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (15)
XL
Xiaozhen Li
LL
Lu Liu
SL
Shengliang Li
YW
Yingpeng Wan
JC
Jia-Xiong Chen
ST
Shuang Tian
ZH
Zhongming Huang
YX
Ya-Fang Xiao
XC
Xiao Cui
CX
Chengyang Xiang
QT
Qinglong Tan
XZ
Xiao-Hong Zhang
WG
Weisheng Guo
XL
Xing-Jie Liang
CL
Chun-Sing Lee