Antibiotic
Resistance Genes and Associated Microbial
Community Conditions in Aging Landfill Systems
Version 2 2017-10-19, 20:15
Version 1 2017-10-19, 20:14
Posted on 2017-10-19 - 20:15
Landfills receive about 350 million
tons of municipal solid wastes
(MSWs) per year globally, including antibiotics and other coselecting
agents that impact antimicrobial resistance (AMR). However, little
is known about AMR in landfills, especially as a function of landfill
ages. Here we quantified antibiotics, heavy metals, and AMR genes
(ARGs) in refuse and leachates from landfills of different age (<3,
10, and >20 years). Antibiotics levels were consistently lower
in
refuse and leachates from older landfills, whereas ARG levels in leachates
significantly increased with landfill age (One-way ANOVA, F = 10.8, P < 0.01). Heavy metals whose contents increased as landfills
age (one-way ANOVA, F = 12.3, P < 0.01) were significantly
correlated with elevated levels of ARGs (Mantel test, R = 0.66, P < 0.01) in leachates, which implies
greater AMR exposure risks around older landfills. To further explain
ARGs distributional mechanisms with age, microbial communities, mobile
genetic elements (MGEs) and environmental factors were contrasted
between refuse and leachate samples. Microbial communities in the
refuse were closely correlated with ARG contents (Procrustes test; M2 = 0.37, R = 0.86, P < 0.001), whereas ARG in leachates were more associated
with MGEs.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Wu, Dong; Huang, Xing-Hua; Sun, Jin-Zhao; Graham, David W.; Xie, Bing (2017). Antibiotic
Resistance Genes and Associated Microbial
Community Conditions in Aging Landfill Systems. ACS Publications. Collection. https://doi.org/10.1021/acs.est.7b03797
or
Select your citation style and then place your mouse over the citation text to select it.
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (5)
DW
Dong Wu
XH
Xing-Hua Huang
JS
Jin-Zhao Sun
DG
David W. Graham
BX
Bing Xie
KEYWORDS
coselecting agentsAntibiotic Resistance GenesAMR exposure risksAMR genesM 2Procrustes testAging Landfill Systems LandfillsOne-way ANOVAMGEimpact antimicrobial resistanceARGs distributional mechanismsARG contentsMicrobial communitiesleachate samplesMantel testAntibiotics levelsMSWAssociated Microbial Community ConditionsARG levels20 yearslandfill agelandfills agelandfill ages