An Efficient Diamine·Copper
Complex-Catalyzed Coupling of
Arylboronic Acids with Imidazoles
Posted on 2000-04-13 - 00:00
A novel diamine·copper complex-catalyzed intermolecular coupling of arylboronic acids (1) with imidazoles (3) is described. In the presence
of a catalytic amount of [Cu(OH)·TMEDA]2Cl2 (2), arylboronic acids (1) react smoothly with imidazoles (3) in dichloromethane at room temperature
to give a variety of N-arylimidazoles (4) in good to excellent yields.
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Collman, James P.; Zhong, Min (2016). An Efficient Diamine·Copper
Complex-Catalyzed Coupling of
Arylboronic Acids with Imidazoles. ACS Publications. Collection. https://doi.org/10.1021/ol000033j