A Flexible Route to (5R)-Thiolactomycin,
a Naturally Occurring Inhibitor of Fatty
Acid Synthesis
Posted on 2002-10-08 - 00:00
A new and efficient asymmetric synthesis of naturally occurring (5R)-thiolactomycin (1) using d-alanine as the source of chirality is described.
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McFadden, Jill M.; Frehywot, Gojeb L.; Townsend, Craig A. (2016). A Flexible Route to (5R)-Thiolactomycin,
a Naturally Occurring Inhibitor of Fatty
Acid Synthesis. ACS Publications. Collection. https://doi.org/10.1021/ol026685k