Xavier Michalet

Publications

• In vitro and in vivo phasor analysis of stoichiometry and pharmacokinetics using near-infrared dyes
• Lighting Up Individual DNA Binding Proteins with Quantum Dots
• High Affinity scFv-Hapten Pair as a Tool for Quantum Dot Labeling and Tracking of Single Proteins in Live Cells
• Detectors for single-molecule fluorescence imaging and spectroscopy
• Equilibrium shape degeneracy in starfish vesicles.
• Nanometer Distance Measurements between Multicolor Quantum Dots
• High Speed Multichannel Charge Sensitive Data Acquisition System With Self-Triggered Event Timing
• Mean square displacement analysis of single-particle trajectories with localization error: Brownian motion in an isotropic medium
• Measuring diffusion with polarization-modulation dual-focus fluorescence correlation spectroscopy
• Microchannel plate imaging photon counters for ultraviolet through NIR detection with high time resolution
• Optimal diffusion coefficient estimation in single-particle tracking
• Phasor-based single-molecule fluorescence lifetime imaging using a wide-field photon-counting detector
• Ultra high-throughput single molecule spectroscopy with a 1024 pixel SPAD
• Single-molecule fluorescence spectroscopy and imaging
• Photon-HDF5: an open file format for single-molecule fluorescence experiments using photon-counting detectors
• New photon-counting detectors for single-molecule fluorescence spectroscopy and imaging
• Next-generation 3-D detector improves single-molecule imaging
• Parallel multispot smFRET analysis using an 8-pixel SPAD array
• Phasor imaging with a widefield photon-counting detector
• Single-Quantum Dot Imaging with a Photon Counting Camera
• Suppression of quantum dot blinking in DTT-doped polymer films
• TRACKING SINGLE PROTEINS IN LIVE CELLS USING SINGLE-CHAIN ANTIBODY FRAGMENT-FLUORESCENT QUANTUM DOT AFFINITY PAIR
• Mean square displacement analysis of single-particle trajectories with localization error: Brownian motion in an isotropic medium (vol 82, 041914, 2010)
• Continuous and discrete phasor analysis of binned or time-gated periodic decays
• The FRET-based structural dynamics challenge -- community contributions to consistent and open science practices
• In vivo quantitative FRET small animal imaging: Intensity versus lifetime-based FRET
• in vivoquantitative FRET small animal imaging: intensity versus lifetime-based FRET
• Multispot single-molecule FRET: high-throughput analysis of freely diffusing molecules
• High-throughput smFRET analysis of freely diffusing nucleic acid molecules and associated proteins
• Single Photon, Time-Gated, Phasor-based Fluorescence Lifetime Imaging Through Highly Scattering Medium
• Hybrid photodetector for single-molecule spectroscopy and microscopy - art. no. 68620F
• Development of new photon-counting detectors for single-molecule fluorescence microscopy
• Dynamic Partitioning of a Glycosyl-Phosphatidylinositol-Anchored Protein in Glycosphingolipid-Rich Microdomains Imaged by Single-Quantum Dot Tracking
• High-throughput FCS using an LCOS spatial light modulator and an 8 x 1 SPAD array
• High-throughput multispot single-molecule spectroscopy
• High-throughput single-molecule fluorescence spectroscopy using parallel detection
• FRETBursts: An Open Source Toolkit for Analysis of Freely-Diffusing Single-Molecule FRET
• Multispot single-molecule FRET: High-throughput analysis of freely diffusing molecules
• Towards measurements of absolute membrane potential in Bacillus subtilis using fluorescence lifetime
• A Novel Initiation Pathway inEscherichia ColiTranscription
• Optical crosstalk in SPAD arrays for high-throughput single-molecule fluorescence spectroscopy
• 48-spot single-molecule FRET setup with periodic acceptor excitation
• Toward dynamic structural biology: Two decades of single-molecule Förster resonance energy transfer
• Different types of pausing modes during transcription initiation
• In vitro and in vivo phasor analysis of stoichiometry and pharmacokinetics using short‐lifetime near‐infrared dyes and time‐gated imaging
• A 512 × 512 SPAD Image Sensor With Integrated Gating for Widefield FLIM
• Wide-field time-gated SPAD imager for phasor-based FLIM applications
• Wide-field time-gated SPAD imager for phasor-based FLIM applications
• Continuous and discrete phasor analysis of binned or time-gated periodic decays
• 48-spot single-molecule FRET setup with periodic acceptor excitation
• Single-molecule spectroscopy and microscopy
• Protein-protein interactions as a tool for site-specific labeling of proteins
• Stretching Single-Stranded DNA on a Surface
• Ultrahigh-Resolution Colocalization of Spectrally Separable Point-like Fluorescent Probes
• Vesicles of Toroidal Topology: Observed Morphology and Shape Transformations
• Fluctuating vesicles of nonspherical topology
• Fluorescence lifetime microscopy with a time- and space-resolved single-photon counting detector
• A space- and time-resolved single-photon counting detector for fluorescence microscopy and spectroscopy - art. no. 60920M
• Chemical physics - Single-molecule spectroscopy comes of age
• Development of an ultrafast single photon counting imager for single molecule imaging
• Single-Molecule Fluorescence Studies of Protein Folding and Conformational Dynamics
• Accurate FRET measurements within single diffusing biomolecules using alternating-laser excitation
• Advances in fluorescence imaging with quantum dot bio-probes
• Cross delay line detectors for high time resolution astronomical polarimetry and biological fluorescence imaging
• DNA molecular combing. Physical mapping and genetic diagnostics
• Molecular combing: A high-resolution technique
• Near-infrared peptide-coated quantum dots for small animal imaging - art. no. 60960B
• New light on quantum dot cytotoxicity
• High-resolution mapping of the X-linked lymphoproliferative syndrome region by FISH on combed DNA
• OBSERVATION OF STABLE SHAPES AND CONFORMAL DIFFUSION IN GENUS-2 VESICLES
• Photon-counting H33D detector for biological fluorescence imaging
• Properties of fluorescent semiconductor nanocrystals and their application to biological labeling
• Quantifying single gene copy number by measuring fluorescent probe lengths on combed genomic DNA
• Quantifying single gene copy number by measuring fluorescent probe lengths on combed genomic DNA (vol 97, pg 222, 2000)
• Ultrahigh-resolution colocalization of spectrally separable point-like fluorescent probes
• Ultrahigh-resolution multicolor colocalization of single fluorescent probes
• Peptide-coated semiconductor nanocrystals for biomedical applications
• Peptide Coated Quantum Dots for Biological Applications
• Ultrahigh-resolution multicolor colocalization of single fluorescent nanocrystals
• Quantum dots for live cells, in vivo imaging, and diagnostics
• Shot-noise limited single-molecule FRET histograms: Comparison between theory and experiments
• Wavefunction engineering: From quantum wells to near-infrared type-II colloidal quantum dots synthesized by layer-by-layer colloidal epitaxy
• Periodic acceptor excitation spectroscopy of single molecules
• THE PHYSICS OF LIPOSOMES
• The power and prospects of fluorescence microscopies and spectroscopies
• Using photon statistics to boost microscopy resolution
• Dynamic molecular combing: Stretching the whole human genome for high-resolution studies
• Femtomole mixer for microsecond kinetic studies of protein folding