Theo Portlock

Publications

• Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation
• Integrative functional analysis uncovers metabolic differences between Candida species
• GutMicroNet: An interactive platform for gut microbiome interaction exploration
• Structure and functional analysis of the Legionella chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation
• Type II secretion-dependent aminopeptidase lapa and acyltransferase plac are redundant for nutrient acquisition during Legionella pneumophila intracellular infection of amoebas
• Structure, Dynamics and Cellular Insight Into Novel Substrates of the Legionella pneumophila Type II Secretion System
• Multi-omics analyses reveal multimodal Fusobacterium DNA damage perturbations in colorectal cancer
• Faecal microbiota transplant restores intestinal barrier function and augments ammonia metabolism in patients with cirrhosis: a randomised single-blind placebo-controlled trial
• Gut Microbial Dysbiosis in Myeloid Neoplasms: Correlations with Clinical and Genomic Features
• The infant gut microbiome and cognitive development in malnutrition
• Clinical, experimental and pathophysiological effects of Yaq-001: a non-absorbab le, gut-restricted adsorbent in models and patients with cirrhosis
• The Legionella collagen-like protein employs a distinct binding mechanism for the recognition of host glycosaminoglycans
• Early life microbial succession in the gut follows common patterns in humans across the globe
• Global compositional and functional states of the human gut microbiome in health and disease
• Code error in Wang H, Avillach P. “Diagnostic Classification and Prognostic Prediction Using Common Genetic Variants in Autism Spectrum Disorder: Genotype-Based Deep Learning.” (Preprint)
• Interconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognition
• A review of model evaluation metrics for machine learning in genetics and genomics.
• Response to Letter to Editor: Comment on "The infant gut microbiome and cognitive development in malnutrition".
• Fecal microbiota transplantation alters gut phage communities in a clinical trial for obesity.
• Alterations in gut microbiota composition, plasma lipids, and brain activity, suggest inter-connected pathways influencing malnutrition-associated cognitive and neurodevelopmental changes.
• TheLegionellacollagen-like protein employs a unique binding mechanism for the recognition of host glycosaminoglycans
• Substrate recognition by the Legionella pneumophila Type II Secretion System
• Sex-dependent prediction of autism