Sehyun Oh

Publications

• Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma
• Global Alliance for Genomics and Health Meets Bioconductor: Toward Reproducible and Agile Cancer Genomics at Cloud Scale.
• Reliable Analysis of Clinical Tumor-Only Whole-Exome Sequencing Data.
• Cancer Health Impact Program (CHIP): Identifying Social and Demographic Associations of mHealth Access and Cancer Screening Behaviors Among Brooklyn, New York, Residents.
• Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.
• Escape from telomere-driven crisis is DNA ligase III dependent.
• The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining.
• DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells.
• Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity.
• Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage.
• Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction.
• Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends.
• Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic cells
• Multiomic Integration of Public Oncology Databases in Bioconductor
• GenomicSuperSignature: interpretation of RNA-seq experiments through robust, efficient comparison to public databases
• HGNChelper: identification and correction of invalid gene symbols for human and mouse
• GenomicSuperSignature facilitates interpretation of RNA-seq experiments through robust, efficient comparison to public databases
• Data from Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma
• Supplementary Data from Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma
• AnVILWorkflow: A runnable workflow package for Cloud-implemented bioinformatics analysis pipelines [version 1; peer review: awaiting peer review]
• lefser: Implementation of metagenomic biomarker discovery tool, LEfSe, in R
• Commonly used compositional data analysis implementations are not advantageous in microbial differential abundance analyses benchmarked against biological ground truth