Rongqun Guo

Publications

• Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors
• T cell regeneration: an update on progress and challenges
• RECONSTITUTION OF T LYMPHOPOIESIS FROM PLURIPOTENT STEM CELLS BY DEFINED TRANSCRIPTION FACTORS
• 1023-REGENERATION OF T LYMPHOPOIESIS FROM PLURIPOTENT STEM CELLS BY DEFINED FACTORS
• Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors
• Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes
• Single-cell expression profiles of ACE2 and TMPRSS2 reveals potential vertical transmission and fetus infection of SARS-CoV-2.
• Erythroblastic Island Macrophages Shape Normal Erythropoiesis and Drive Associated Disorders in Erythroid Hematopoietic Diseases
• Single-cell map of diverse immune phenotypes in the acute myeloid leukemia microenvironment
• Exosomes from BM-MSCs promote acute myeloid leukemia cell proliferation, invasion and chemoresistance via upregulation of S100A4
• SGK1, a Critical Regulator of Immune Modulation and Fibrosis and a Potential Therapeutic Target in Chronic Graft-Versus-Host Disease
• Single-Cell Analysis of Target Antigens of CAR-T Reveals a Potential Landscape of “On-Target, Off-Tumor Toxicity”
• Generation and clinical potential of functional T lymphocytes from gene-edited pluripotent stem cells
• Evidence of pyroptosis and ferroptosis extensively involved in autoimmune diseases at the single-cell transcriptome level.
• Targeting macrophages in hematological malignancies: recent advances and future directions.
• Effects of post-transplant maintenance therapy with decitabine prophylaxis on the relapse for acute lymphoblastic leukemia.
• CCL17 acts as an antitumor chemokine in micromilieu‐driven immune skewing
• Unbiased Single‐Cell Sequencing of Hematopoietic and Immune Cells from Aplastic Anemia Reveals the Contributors of Hematopoiesis Failure and Dysfunctional Immune Regulation
• Targeted single-cell RNA sequencing analysis reveals metabolic reprogramming and the ferroptosis-resistant state in hematologic malignancies.
• Histone lysine demethylase KDM5B facilitates proliferation and suppresses apoptosis in human acute myeloid leukemia cells through the miR-140-3p/BCL2 axis.
• Histone lysine demethylase KDM5B facilitates proliferation and suppresses apoptosis in human acute myeloid leukemia cells through the miR-140-3p/BCL2 axis
• Dysregulated T-cell homeostasis and decreased CD30+ Treg proliferating in aplastic anemia
• Multi-omics analysis reveals a feedback loop amplifying immune responses in acute graft-versus-host disease due to imbalanced gut microbiota and bile acid metabolism
• Optimizing CAR-T cell Culture: Differential effects of IL-2, IL-12, and IL-21 on CAR-T cells.
• Exosome-Mediated Lectin Pathway and Resistin-MIF-AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia.