Rance Nault

Publications

• Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose–response study designs
• Genome-Wide ChIPseq Analysis of AhR, COUP-TF, and HNF4 Enrichment in TCDD-Treated Mouse Liver
• Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo-p-dioxin
• A Case for Accelerating Standards to Achieve the FAIR Principles of Environmental Health Research Experimental Data
• Single-cell transcriptomics shows dose-dependent disruption of hepatic zonation by TCDD in mice
• Analysis of Cell–Cell Communication by Single-Nuclei RNA Sequencing Identifies AHR-Mediated Induction of NRG-ERBB Signaling
• Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose-response study designs
• Cystine/Glutamate Xc– Antiporter Induction Compensates for Transsulfuration Pathway Repression by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) to Ensure Cysteine for Hepatic Glutathione Biosynthesis
• Generative Modeling of Single Cell Gene Expression for Dose-Dependent Chemical Perturbations
• A Cell Atlas of Thoracic Aortic Perivascular Adipose Tissue: a focus on mechanotransducers
• How single-cell transcriptomics provides insight on hepatic responses to TCDD
• Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice
• Dose-dependent disruption of hepatic zonation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice: integration of single-nuclei RNA sequencing and spatial transcriptomics
• 2,3,7,8-Tetrachlorodibenzo-p-dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice
• A toxicogenomic approach for the risk assessment of the food contaminant acetamide
• Application of single nuclei RNA sequencing to assess the hepatic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin
• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters hepatic polyunsaturated fatty acid metabolism and eicosanoid biosynthesis in female Sprague-Dawley rats
• Single-Nuclei RNA Sequencing Assessment of the Hepatic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin
• Genetics-Based Approach to Identify Novel Genes Regulated by the Aryl Hydrocarbon Receptor in Mouse Liver
• A cell atlas of thoracic aortic perivascular adipose tissue: a focus on mechanotransducers
• Early life adversity promotes gastrointestinal dysfunction through a sex-dependent phenotypic switch in enteric glia
• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) elicited dose-dependent shifts in the murine urinary metabolome associated with hepatic AHR-mediated differential gene expression
• Mechanotransduction in the Perivascular Adipose Tissue
• Single-nucleus analysis of thoracic perivascular adipose tissue reveals critical changes in cell composition, communication, and gene regulatory networks induced by a high fat hypertensive diet