Michael Marty

Publications

• A Universal Score for Deconvolution of Intact Protein and Native Electrospray Mass Spectra
• Assembly of Model Membrane Nanodiscs for Native Mass Spectrometry
• UniDecCD: Deconvolution of Charge Detection-Mass Spectrometry Data
• GNPS Dashboard: collaborative exploration of mass spectrometry data in the web browser
• Investigating Antimicrobial Peptide–Membrane Interactions Using Fast Photochemical Oxidation of Peptides in Nanodiscs
• Fourier-Transform Approach for Reconstructing Macromolecular Mass Defect Profiles
• Correction to Copper-Free Click Enabled Triazabutadiene for Bioorthogonal Protein Functionalization
• Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
• Surface Modified Nano-Electrospray Needles Improve Sensitivity for Native Mass Spectrometry
• Lipids and EGCG Affect α-Synuclein Association and Disruption of Nanodiscs
• Investigating the Lipid Selectivity of Membrane Proteins in Heterogeneous Nanodiscs
• Influenza AM2 Channel Oligomerization Is Sensitive to Its Chemical Environment
• Investigating Daptomycin-Membrane Interactions Using Native MS and Fast Photochemical Oxidation of Peptides in Nanodiscs
• Deconvolving Native and Intact Protein Mass Spectra with UniDec
• Lipids and Small Molecules Affect α-synuclein Association and Disruption of Nanodiscs
• Direct-MS analysis of antibody-antigen complexes
• Investigating Daptomycin–Membrane Interactions Using Native MS and Fast Photochemical Oxidation of Peptides in Nanodiscs
• Eliminating Artifacts in Electrospray Deconvolution with a SoftMax Function
• Illuminating Individual Membrane Protein Complexes with Mass Photometry
• Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L
• Structural basis of omega-3 fatty acid transport across the blood-brain barrier
• Front Cover: Albumin Conjugates of Thiosemicarbazone and Imidazole‐2‐thione Prochelators: Iron Coordination and Antiproliferative Activity (ChemMedChem 18/2021)
• Nanodiscs and Mass Spectrometry: Making Membranes Fly
• Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis.
• Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors.
• Fundamentals: How Do We Calculate Mass, Error, and Uncertainty in Native Mass Spectrometry?
• Copper-Free Click Enabled Triazabutadiene for Bioorthogonal Protein Functionalization
• Guest Editorial: Bias in Mass Spectrometry Technical Support
• A unique class of Zn2+-binding PBPs underlies cephalosporin resistance and sporogenesis of Clostridioides difficile
• Protein Modification via Mild Photochemical Isomerization of Triazenes to Release Aryl Diazonium Ions
• Investigating Daptomycin-Membrane Interactions Using Native MS and Fast Photochemical Oxidation of Peptides in Nanodiscs
• Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay
• Native mass spectrometry for structural biology: A perspective
• Lipid tails modulate antimicrobial peptide membrane incorporation and activity
• Interspecies Variation Affects IAPP Membrane Binding
• Surface Modified Nano-Electrospray Needles Improve Sensitivity for Native Mass Spectrometry
• Imidazole Derivatives Improve Charge Reduction and Stabilization for Native Mass Spectrometry
• A Universal Score for Deconvolution of Intact Protein and Native Electrospray Mass Spectra
• Scratching the surface: native mass spectrometry of peripheral membrane protein complexes
• Measuring Remodeling of the Lipid Environment Surrounding Membrane Proteins with Lipid Exchange and Native Mass Spectrometry
• Revealing the Specificity of a Range of Antimicrobial Peptides in Lipid Nanodiscs by Native Mass Spectrometry
• Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, and Shikonin Are Nonspecific Promiscuous SARS-CoV-2 Main Protease Inhibitors
• Native Mass Spectrometry of Membrane Proteins
• Native mass spectrometry reveals the simultaneous binding of lipids and zinc to rhodopsin
• Probing the structure of nanodiscs using surface-induced dissociation mass spectrometry
• Suzuki Coupling of Protected Aryl Diazonium Ions: Expanding the Knowledge of Triazabutadiene Compatible Reactions
• Assembly of Model Membrane Nanodiscs for Native Mass Spectrometry
• Albumin Conjugates of Thiosemicarbazone and Imidazole‐2‐thione Prochelators: Iron Coordination and Antiproliferative Activity
• Structural and mechanistic insights into amyloid‐β and α‐synuclein fibril formation and polyphenol inhibitor efficacy in phospholipid bilayers
• Investigating the Lipid Selectivity of Membrane Proteins in Heterogeneous Nanodiscs
• High-resolution mass spectrometry of small molecules bound to membrane proteins
• Probing the Lipid Annular Belt by Gas-Phase Dissociation of Membrane Proteins in Nanodiscs
• Simulating a time-of-flight mass spectrometer: A labview exercise
• Validating Enterovirus D68-2Apro as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2Apro Inhibitor.
• Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions
• Native Mass Spectrometry Characterization of Intact Nanodisc Lipoprotein Complexes
• Nonlinear Analyte Concentration Gradients for One-Step Kinetic Analysis Employing Optical Microring Resonators
• Ultra-thin layer MALDI mass spectrometry of membrane proteins in nanodiscs
• The effect of detergent, temperature, and lipid on the oligomeric state of MscL constructs: Insights from mass spectrometry
• Bayesian deconvolution of mass and ion mobility spectra: From binary interactions to polydisperse ensembles
• Nanodisc-solubilized membrane protein library reflects the membrane proteome
• Combining tandem mass spectrometry with ion mobility separation to determine the architecture of polydisperse proteins
• Interpretation and deconvolution of nanodisc native mass spectra
• Interfacing lipid bilayer nanodiscs and silicon photonic sensor arrays for multiplexed protein-lipid and protein-membrane protein interaction screening
• Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer’s-Associated Aβ Oligomers
• A sliding selectivity scale for lipid binding to membrane proteins
• Unraveling the Composition and Behavior of Heterogeneous Lipid Nanodiscs by Mass Spectrometry
• Engineering Nanodisc Scaffold Proteins for Native Mass Spectrometry
• Interfacing Membrane Mimetics with Mass Spectrometry
• Dissecting the role of the CRMP2–neurofibromin complex on pain behaviors
• MetaUniDec: High-Throughput Deconvolution of Native Mass Spectra
• Rapid LC–MS Method for Accurate Molecular Weight Determination of Membrane and Hydrophobic Proteins
• Chemical Additives Enable Native Mass Spectrometry Measurement of Membrane Protein Oligomeric State within Intact Nanodiscs
• Expanding the Types of Lipids Amenable to Native Mass Spectrometry of Lipoprotein Complexes
• Native Mass Spectrometry of Antimicrobial Peptides in Lipid Nanodiscs Elucidates Complex Assembly
• What’s the Defect? Using Mass Defects to Study Oligomerization of Membrane Proteins and Peptides in Nanodiscs with Native Mass Spectrometry
• Interspecies Variation Affects Islet Amyloid Polypeptide Membrane Binding
• Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L
• Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are non-specific promiscuous SARS-CoV-2 main protease inhibitors
• The UniDec Processing Pipeline for Rapid Analysis of Biotherapeutic Mass Spectrometry Data
• Do Nanodisc Assembly Conditions Affect Natural Lipid Uptake?
• Online Buffer Exchange Enables Automated Membrane Protein Analysis by Native Mass Spectrometry
• Identifying Membrane Protein-Lipid Interactions with Lipidomic Lipid Exchange-Mass Spectrometry
• Characterizing Adeno-Associated Virus Capsids with both Denaturing and Intact Analysis Methods
• Double and triple thermodynamic mutant cycles reveal the basis for specific MsbA-lipid interactions
• UniDec Processing Pipeline for Rapid Analysis of Biotherapeutic Mass Spectrometry Data
• What’s the defect? Using mass defects to study oligomerization of membrane proteins and peptides in nanodiscs with native mass spectrometry
• Combining native mass spectrometry and lipidomics to uncover specific membrane protein–lipid interactions from natural lipid sources
• Differences in Oligomerization of the SARS-CoV-2 Envelope Protein, Poliovirus VP4, and HIV Vpu
• High-Throughput Deconvolution of Native Protein Mass Spectrometry Imaging Data Sets for Mass Domain Analysis
• Identifying Membrane Protein–Lipid Interactions with Lipidomic Lipid Exchange-Mass Spectrometry
• Simultaneous Native Mass Spectrometry Analysis of Single and Double Mutants to Probe Lipid Binding to Membrane Proteins
• Characterizing Adeno-Associated Virus Capsids with Both Denaturing and Intact Analysis Methods
• The 2023 ASMS Sanibel Conference on Membrane Proteins and Their Complexes
• Coupling online size exclusion chromatography with charge detection-mass spectrometry using Hadamard transform multiplexing
• Simultaneous Native Mass Spectrometry Analysis of Single and Double Mutants To Probe Lipid Binding to Membrane Proteins
• UniChromCD for Demultiplexing Time-resolved Charge Detection-Mass Spectrometry Data
• Membrane Proteins: Challenging Biotherapeutic Targets
• UniChromCD for Demultiplexing Time-Resolved Charge Detection-Mass Spectrometry Data
• Coupling Online Size Exclusion Chromatography with Charge Detection-Mass Spectrometry Using Hadamard Transform Multiplexing
• Alanine Scanning to Define Membrane Protein-Lipid Interaction Sites Using Native Mass Spectrometry
• Combining Fourier Transform Ion Mobility with Charge Detection Mass Spectrometry for the Analysis of Multimeric Protein Complexes
• UnidecNMR: automatic peak detection for NMR spectra in 1-4 dimensions
• Navigating the Postdoc Experience
• A Fast Neural Network for Isotopic Charge State Assignment
• Alanine Scanning to Define Membrane Protein–Lipid Interaction Sites Using Native Mass Spectrometry