Leonardo de Assis

Publications

• Opsins outside the eye and the skin: a more complex scenario than originally thought for a classical light sensor
• The function, mechanisms, and role of the genes PTEN and TP53 and the effects of asbestos in the development of malignant mesothelioma: a review focused on the genes' molecular mechanisms.
• Authors’ reply | Resposta dos autores
• Antagonists of the Mineralocorticoid Receptor or A New Pharmacological Class?
• The circadian clock and metabolic homeostasis: entangled networks
• Pre- and post-conditioning of the heart: an overview of cardioprotective signaling pathways
• A Utilização de Vídeos no Ensino: Uma Experiência Prática com Alunos de Graduação
• Melanopsin, a Canonical Light Receptor, Mediates Thermal Activation of Clock Genes.
• Cold-sensing TRPM8 channel participates in circadian control of the brown adipose tissue.
• Melanopsin and rhodopsin mediate UVA-induced immediate pigment darkening: Unravelling the photosensitive system of the skin
• Novel light‐dependent and light‐independent functions of opsin 5
• Non-Metastatic Cutaneous Melanoma Induces Chronodisruption in Central and Peripheral Circadian Clocks.
• Expression of the Circadian Clock Gene BMAL1 Positively Correlates With Antitumor Immunity and Patient Survival in Metastatic Melanoma
• The effect of white light on normal and malignant murine melanocytes: A link between opsins, clock genes, and melanogenesis.
• Non-genomic effects of spironolactone and eplerenone in cardiomyocytes of neonatal Wistar rats: do they evoke cardioprotective pathways?
• The molecular clock in the skin, its functionality, and how it is disrupted in cutaneous melanoma: a new pharmacological target?
• Estradiol differently affects melanin synthesis of malignant and normal melanocytes: a relationship with clock and clock-controlled genes
• Swimming training promotes cardiac remodeling and alters the expression of mRNA and protein levels involved in calcium handling in hypertensive rats.
• The role of key genes and pathways involved in the tumorigenesis of Malignant Mesothelioma
• Overview of the biochemical and genetic processes in malignant mesothelioma.
• Calcium handling proteins: structure, function, and modulation by exercise.
• Rapid effects of aldosterone in primary cultures of cardiomyocytes – do they suggest the existence of a membrane-bound receptor?
• Heat shock antagonizes UVA-induced responses in murine melanocytes and melanoma cells: an unexpected interaction
• Melanopsin mediates UVA-dependent modulation of proliferation, pigmentation, apoptosis, and molecular clock in normal and malignant melanocytes
• Mineralocorticoid receptor antagonists lead to increased adenosine bioavailability and modulate contractile cardiac parameters
• An Immunometabolic Shift Modulates Cytotoxic Lymphocyte Activation During Melanoma Progression in TRPA1 Channel Null Mice.
• Thermal stress in Danio rerio: A link between temperature, light, thermo-TRP channels, and clock genes
• Genomic and rapid effects of aldosterone: what we know and do not know thus far
• TRPV1 participates in the activation of clock molecular machinery in the brown adipose tissue in response to light-dark cycle.
• How does the skin sense sun light? An integrative view of light sensing molecules
• Comments regarding Hiramoto et al.
• Loss of Melanopsin (OPN4) Leads to a Faster Cell Cycle Progression and Growth in Murine Melanocytes
• Spironolactone and eplerenone are cardioprotective during early phase of ischemia in rats submitted to acute coronary occlusion
• The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1—A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting
• Rewiring of liver diurnal transcriptome rhythms by triiodothyronine (T3) supplementation
• Melanopsin (Opn4) is an oncogene in cutaneous melanoma
• Proanthocyanidins Restore the Metabolic Diurnal Rhythm of Subcutaneous White Adipose Tissue According to Time-Of-Day Consumption
• Lack of TRPV1 Channel Modulates Mouse Gene Expression and Liver Proteome with Glucose Metabolism Changes
• Grape-seed proanthocyanidin extract (GSPE) modulates diurnal oscillations of key hepatic metabolic genes and metabolites alleviating hepatic lipid deposition in cafeteria-fed obese rats in a time-of-day-dependent manner
• The role of the circadian clock in the development, progression, and treatment of non‐alcoholic fatty liver disease
• Melanopsin expression in the retinas of owls with different daily activity patterns
• The trophoblast clock controls transport across placenta in mice
• CasEcR and CasMIH Genes in the Blue Crab, Callinectes sapidus: A Temporal Evaluation and Melatonin Effects
• Low Temperature Effect on the Endocrine and Circadian Systems of Adult Danio rerio
• Melanoma affects clock gene machinery of several organs in tumor-bearing mice
• Non-alcoholic steatohepatitis disrupts diurnal liver transcriptome rhythms in mice
• Opsins as main regulators of skin biology
• Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice
• Chronic Inflammation Disrupts Circadian Rhythms in Splenic CD4+ and CD8+ T Cells in Mice
• Thyroid hormone receptor beta (THRB) dependent regulation of diurnal hepatic lipid metabolism in adult male mice
• The epidermal circadian clock integrates and subverts brain signals to guarantee skin homeostasis
• Non-rhythmic modulators of the circadian system: A new class of circadian modulators
• Light-specific wavelengths differentially affect the exploration rate, opercular beat, skin color change, opsin transcripts, and the oxi-redox system of the longsnout seahorse Hippocampus reidi
• Melanopsin (OPN4) is a novel player in skin homeostasis and attenuates UVA-induced effects
• Circadian Gating of Thyroid Hormone Action in Hepatocytes
• Author Correction: Thyroid hormone receptor beta (THRB) dependent regulation of diurnal hepatic lipid metabolism in adult male mice
• Circadian de(regulation) in physiology: implications for disease and treatment
• Glaucoma‐inducing retinal ganglion cell degeneration alters diurnal rhythm of key molecular components of the central clock and locomotor activity in mice
• Grape‐Seed Proanthocyanidin Extract (GSPE) Modulates Diurnal Rhythms of Hepatic Metabolic Genes and Metabolites, and Reduces Lipid Deposition in Cafeteria‐Fed Rats in a Time‐of‐Day‐Dependent Manner
• Stage-specific phenotypic and transcriptional alterations in keratinocytes exposed to acute and chronic blue light
• Endocrine regulation of circadian rhythms
• Stage‐specific phenotypic and transcriptional alterations in HaCaT keratinocytes exposed to acute and chronic blue light
• Grape seed procyanidins modulate PER2 circadian rhythm and lipid metabolism of white adipose tissue explants in a time-dependent manner