John Konhilas

Publications

• Estradiol Activates AMPK through Interaction with Estrogen Receptor Beta
• Myosin Myopathies
• Sex Dimorphic Myofilament Function and AMPK Expression in R403Q Hearts
• Phytoestrogens and the Role in Cardiovascular Health
• The R403Q Mutation Alters Isometric and Energetic Properties in 2 Month Mice
• The Role of MEKK1 in Hypertrophic Cardiomyopathy
• Cognitive impairment in heart failure: A protective role for angiotensin-(1-7).
• Cardiac-specific knockout of Lmod2 results in a severe reduction in myofilament force production and rapid cardiac failure
• A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
• Micro-RNA-195 and -451 Regulate the LKB1/AMPK Signaling Axis by Targeting MO25
• Reduced Length-Dependent Activation in Human Cardiomyocytes Harboring the Troponin I Mutation R145W
• Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice
• Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse
• Menopause Impairs Cardiovascular Resilience and Blood Pressure Regulation
• Sex dimorphisms of crossbridge cycling kinetics in transgenic hypertrophic cardiomyopathy mice
• Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy
• A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction
• Diet and sex modify exercise and cardiac adaptation in the mouse
• AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy
• Remodeling the cardiac transcriptional landscape with diet
• What makes a dead cell attractive?
• Probiotic Species on Cardiovascular Disease
• The complex nature of oestrogen signalling in breast cancer: enemy or ally?
• Inherited Cardiomyopathies: From Genotype to Phenotype
• What We Know and Do Not Know about Sex and Cardiac Disease
• Cardiac Troponin I Phosphorylation at ser149 by Protein Kinase A: A Potential Modulator of Myocardial Contractility
• LKB1 and MO25 Demonstrate Significant Interaction with Myofilament Proteins
• The Interaction of AMP-Activated Protein Kinase and its Upstream Activator, Lkb1/Mo25/Strad, Modifies Contractile Function in Rat Cardiac Trabeculae
• LKB1/Mo25/STRAD Uniquely Impacts Sarcomeric Contractile Function and Posttranslational Modification
• First in Man: Adipose-derived Stromal Vascular Fraction Cells May Promote Restorative Cardiac Function
• Oestrogen receptors interact with the α-catalytic subunit of AMP-activated protein kinase
• Molecular Mechanisms Underlying Cardiac Adaptation to Exercise
• Abstract 559: AMP-Activated Protein Kinase And Estrogen-Dependent Mechanisms Underlying Increased Susceptibility To Cardiovascular Disease During Menopause
• Rapid Porcine Lung Decellularization Using a Novel Organ Regenerative Control Acquisition Bioreactor
• Inhibition of Ovarian KIT Phosphorylation by the Ovotoxicant 4-Vinylcyclohexene Diepoxide in Rats1
• Target Specific Phosphorylation of Cardiac Troponin I and Sex Dimorphic Myofilament Function in R403Q Mice
• Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype?
• Contributors
• The impact of post-exercise hydration with deep-ocean mineral water on rehydration and exercise performance
• ANG II-induced hypertension in the VCD mouse model of menopause is prevented by estrogen replacement during perimenopause
• Keeping the beat. Focus on “Enrichment of neonatal rat cardiomyocytes in primary culture facilitates long-term maintenance of contractility in vitro”
• Human Amniotic Membrane Promotes Antimicrobial Microenvironment in a Device-Related Infection
• A dual therapy of off-pump temporary left ventricular extracorporeal device and amniotic stem cell for cardiogenic shock
• Cyclin D2 is a critical mediator of exercise-induced cardiac hypertrophy
• 172. B-Type Natriuretic Peptide Gene Therapy as a Novel Early Treatment for Familial Hypertrophic Cardiomyopathy
• Fluid type influences acute hydration and muscle performance recovery in human subjects
• Estrogenic Compounds Are Not Always Cardioprotective and Can Be Lethal in Males with Genetic Heart Disease
• Improved metabolism and redox state with a novel preservation solution: implications for donor lungs after cardiac death (DCD)
• Liver Kinase B1 complex acts as a novel modifier of myofilament function and localizes to the Z-disk in cardiac myocytes
• Liquefaction of the Brain following Stroke Shares a Similar Molecular and Morphological Profile with Atherosclerosis and Mediates Secondary Neurodegeneration in an Osteopontin-Dependent Mechanism
• Myosin Myopathies
• Partnering Up for Cardiac Hypertrophy
• Regional pulmonary blood flow measurement in humans with electron-beam computed tomography
• The Effects of Biological Sex and Diet on the Development of Heart Failure
• Length-dependent activation in three striated muscle types of the rat
• Myofilament Calcium Sensitivity in Skinned Rat Cardiac Trabeculae
• The significance of linear stress-length maintenance in thin and thick wall elastic spheres
• Cooperative activation in cardiac muscle: impact of sarcomere length
• Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing
• From Sarcomeric Mutations to Heart Disease: Understanding Familial Hypertrophic Cardiomyopathy
• Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions
• Liquefaction of the brain following stroke shares a similar molecular and morphological profile with atherosclerosis and mediates secondary neurodegeneration in an osteopontin dependent mechanism
• Exercise Can Prevent and Reverse the Severity of Hypertrophic Cardiomyopathy
• Frank-Starling law of the heart and the cellular mechanisms of length-dependent activation
• Myofilament lattice spacing as a function of sarcomere length in isolated rat myocardium
• Sex modifies exercise and cardiac adaptation in mice
• Loaded wheel running and muscle adaptation in the mouse
• Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise
• Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca2+activation