EB
Publications
- Detection of human adaptation during the past 2,000 years
- High-throughput biochemical profiling reveals Cas9 off-target binding and unbinding heterogeneity
- Reduced signal for polygenic adaptation of height in UK Biobank
- Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements
- High-resolution mapping of cancer cell networks using co-functional interactions
- Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement
- Reduced signal for polygenic adaptation of height in UK Biobank
- Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
- High‐resolution mapping of cancer cell networks using co‐functional interactions
- Junior scientists spotlight social bonds in seminars for diversity, equity, and inclusion in STEM
- Skipper analysis of RNA-protein interactions highlights depletion of genetic variation in translation factor binding sites
- Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement
- De novo Mutations in NALCN Cause a Syndrome of Congenital Contractures of the Limbs and Face with Hypotonia, and Developmental Delay
- De Novo Mutations in NALCN Cause a Syndrome Characterized by Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
- MIPgen: optimized modeling and design of molecular inversion probes for targeted resequencing
- Recurrent de novo mutations implicate novel genes underlying simplex autism risk
- Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia
- Deep sequencing of multiple regions of glial tumors reveals spatial heterogeneity for mutations in clinically relevant genes
- A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer
- Saturation editing of genomic regions by multiplex homology-directed repair
- Germline Missense Variants in the BTNL2 Gene Are Associated with Prostate Cancer Susceptibility
- High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding