Edward Lau

Publications

• Protein prediction models support widespread post-transcriptional regulation of protein abundance by interacting partners
• Harmonizing labeling and analytical strategies to obtain protein turnover rates in intact adult animals
• Simultaneous proteome localization and turnover analysis reveals spatiotemporal dynamics of unfolded protein responses
• Proteogenomics reveals sex-biased aging genes and coordinated splicing in cardiac aging
• Harmonizing Labeling and Analytical Strategies to Obtain Protein Turnover Rates in Intact Adult Animals
• Protein prediction models support widespread post-transcriptional regulation of protein abundance by interacting partners
• Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies
• Proteogenomic characterization of age and sex interactions in cardiac gene expression
• JCAST: Sample-specific protein isoform databases for mass spectrometry-based proteomics experiments
• Combinatorial use of SCX and RP-RP separation for iTRAQ-based quantitative proteomics profiling
• An MRM-based workflow for quantifying cardiac mitochondrial protein phosphorylation in murine and human tissue
• Prioritizing Proteomics Assay Development for Clinical Translation
• Mitochondrial protein turnover: Methods to measure turnover rates on a large scale
• Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation
• Protein kinetic signatures of the remodeling heart following isoproterenol stimulation
• Characterization of human plasma proteome dynamics using deuterium oxide
• Characterization, Design, and Function of the Mitochondrial Proteome: From Organs to Organisms
• Lysine ubiquitination and acetylation of human cardiac 20S proteasomes
• Spatial and temporal dynamics of the cardiac mitochondrial proteome
• N-Linked Glycoprotein Analysis Using Dual-Extraction Ultrahigh-Performance Liquid Chromatography and Electrospray Tandem Mass Spectrometry
• Fully automatable two-dimensional reversed-phase capillary liquid chromatography with online tandem mass spectrometry for shotgun proteomics
• Online combination of reversed-phase/reversed-phase and porous graphitic carbon liquid chromatography for multicomponent separation of proteomics and glycoproteomics samples
• Online coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization
• Combinatorial use of offline SCX and online RP–RP liquid chromatography for iTRAQ-based quantitative proteomics applications
• OsNOA1/RIF1 is a functional homolog of AtNOA1/RIF1: implication for a highly conserved plant cGTPase essential for chloroplast function
• Label-Free Quantitative Proteomics Reveals Survival Mechanisms Developed by Hypertrophic Chondrocytes under ER Stress
• Cyclophilin D and acetylation: A new link in cardiac signaling
• Response to Pomozi et al's research commentary
• Sample preparation for glycoproteins
• ABCC6 localizes to the mitochondria-associated membrane
• Mitochondrial proteome design: From molecular identity to pathophysiological regulation
• Substrate-and Isoform-Specific Proteome Stability in Normal and Stressed Cardiac Mitochondria
• N-linked glycoprotein analysis using dual-extraction ultrahigh-performance liquid chromatography and electrospray tandem mass spectrometry.
• Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart
• Aging models make waves: predicting vascular aging in virtual patients
• Splice junction centric approach to identify translated noncanonical isoforms in the human proteome
• Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity
• Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart
• Atlas of Exosomal microRNAs Secreted From Human iPSC-Derived Cardiac Cell Types
• Transcriptome features of striated muscle aging and predictability of protein level changes
• Transcriptome features of striated muscle aging and predictability of protein level changes
• A Ratiometric Catalog of Protein Isoform Shifts in the Cardiac Fetal Gene Program
• Improved determination of protein turnover rate with heavy water labeling by mass isotopomer ratio selection
• Improved Method to Determine Protein Turnover Rates with Heavy Water Labeling by Mass Isotopomer Ratio Selection