Direk Limmathurotsakul

Publications

• Impact of a multimodal hand hygiene improvement intervention in a 1000-bed hospital in NE Thailand: a stepped wedge clustered randomized controlled trial
• Evaluation of consensus method for the culture of Burkholderia pseudomallei in soil samples from Laos [version 1; referees: 1 approved, 1 approved with reservations]
• Global Burden and Challenges of Melioidosis
• Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC): Supporting the transition from strategy to action [version 1; referees: awaiting peer review]
• Management and outcomes of severe dengue patients presenting with sepsis in a tropical country
• Feasibility and initial outcomes of a multifaceted prevention programme of melioidosis in diabetic patients in Ubon Ratchathani, northeast Thailand
• Clinical epidemiology and outcomes of community acquired infection and sepsis among hospitalized patients in a resource limited setting in Northeast Thailand: A prospective observational study (Ubon-sepsis)
• Misidentification of Burkholderia pseudomallei as Acinetobacter species in northern Thailand
• Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis)
• Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting
• Impact of routine bedside infectious diseases consultation on clinical management and outcome of Staphylococcus aureus bacteraemia in adults
• Comprehensive analysis of clinical Burkholderia pseudomallei isolates demonstrates conservation of unique lipid A structure and TLR4-dependent innate immune activation
• Clinical and molecular epidemiology of Staphylococcus argenteus infections in Thailand
• Extended Loop Region of Hcp1 is Critical for the Assembly and Function of Type VI Secretion System in Burkholderia pseudomallei
• Antibiotic therapy for Staphylococcus aurcus colonised vascular catheter tips and the occurrence of bacteraemia-implications for hospital policy
• Cost-effectiveness analysis of parenteral antimicrobials for acute melioidosis in Thailand
• Consensus on the Development of Vaccines against Naturally Acquired Melioidosis.
• How to Determine the Accuracy of an Alternative Diagnostic Test when It Is Actually Better than the Reference Tests: A Re-Evaluation of Diagnostic Tests for Scrub Typhus Using Bayesian LCMs
• Antimicrobial Disk Susceptibility Testing of Leptospira spp. Using Leptospira Vanaporn Wuthiekanun Agar
• Cost-effectiveness of hand hygiene promotion for MRSA blood stream infection in ICU settings
• Evaluation of Polysaccharide-Based Latex Agglutination Assays for the Rapid Detection of Antibodies to Burkholderia pseudomallei
• Sensitivity and specificity of a lateral flow immunoassay (LFI) in serum samples for diagnosis of melioidosis
• Utility of SOFA score, management and outcomes of sepsis in Southeast Asia: a multinational multicenter prospective observational study
• Leapfrogging laboratories: the promise and pitfalls of high-tech solutions for antimicrobial resistance surveillance in low-income settings
• Clinical Epidemiology of 7,126 Melioidosis Patients in Thailand and the Implications for a National Notifiable Diseases Surveillance System
• Effectiveness of a multifaceted prevention programme for melioidosis in diabetics (PREMEL): a stepped-wedge cluster-randomised controlled trial
• Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis
• Pan-drug-resistant and biofilm-producing strain of Burkholderia pseudomallei: first report of melioidosis from a diabetic patient in Yogyakarta, Indonesia [Letter]
• ‘Antibiotic footprint’ as a communication tool to aid reduction of antibiotic consumption
• Survival of Burkholderia pseudomallei and Pathogenic Leptospira in Cola, Beer, Energy Drinks, and Sports Drinks.
• In vitro passage alters virulence, immune activation and proteomic profiles of Burkholderia pseudomallei.
• Case-Control Study of Use of Personal Protective Measures and Risk for Severe Acute Respiratory Syndrome Coronavirus 2 Infection, Thailand.
• Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-α release in Burkholderia thailandensis infection in vitro.
• A Comparison Between 12 Versus 20 Weeks of Trimethoprim-Sulfamethoxazole as Oral Eradication Treatment for Melioidosis (12vs20): An Open-label, Pragmatic, Multicenter, Non-inferiority, Randomized Controlled Trial.
• Serum From Melioidosis Survivors Diminished Intracellular Burkholderia pseudomallei Growth in Macrophages: A Brief Research Report.
• sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country.
• Antimicrobial Resistance Surveillance in Low- and Middle-Income Countries: Progress and Challenges in Eight South Asian and Southeast Asian Countries.
• Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei.
• Human Immune Responses to Melioidosis and Cross-Reactivity to Low-Virulence Burkholderia Species, Thailand1.
• Multiple phylogenetically-diverse, differentially-virulent Burkholderia pseudomallei isolated from a single soil sample collected in Thailand
• ‘Antibiotic footprint’ as a communication tool to aid reduction of antibiotic consumption—authors’ response
• Barriers and Recommended Interventions to Prevent Melioidosis in Northeast Thailand: A Focus Group Study Using the Behaviour Change Wheel
• Epidemiology and burden of multidrug-resistant bacterial infection in a developing country
• Soil Nutrient Depletion Is Associated with the Presence of Burkholderia pseudomallei
• Improved characterisation of MRSA transmission using within-host bacterial sequence diversity
• Utility of qSOFA and modified SOFA in severe malaria presenting as sepsis
• Early management of sepsis in medical patients in rural Thailand: a single-center prospective observational study
• The utility of an AMR dictionary as an educational tool to improve public understanding of antimicrobial resistance [version 1; peer review: 1 approved]
• Effectiveness of a multifaceted prevention programme for melioidosis in diabetics (PREMEL): A stepped-wedge cluster-randomised controlled trial
• “AMR Dialogues”: a public engagement initiative to shape policies and solutions on antimicrobial resistance (AMR) in Thailand [version 2; peer review: 2 approved]
• NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis
• Impact of infectious diseases consultation on the management of S. aureus bacteraemia in children
• Melioidosis in Africa: should we be looking more closely?(vol 10, pg 273, 2015)
• Subpopulations of Staphylococcus aureus clonal complex 121 are associated with distinct clinical entities
• Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect
• Impaired TLR5 functionality is associated with survival in melioidosis
• A matched case-control study identifies activities of daily living associated with acquisition of melioidosis in northeast Thailand
• Epidemiology, microbiology and mortality associated with community-acquired bacteremia in northeast Thailand: a multicenter surveillance study
• Evaluation of a latex agglutination assay for the identification of Burkholderia pseudomallei and Burkholderia mallei
• Molecular confirmation of co-infection by pathogenic Leptospira spp. and Orientia tsutsugamushi in patients with acute febrile illness in Thailand
• Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand
• Impact of infectious diseases consultation on the management of Staphylococcus aureus bacteraemia in children
• Trimethoprim/sulfamethoxazole resistance in clinical isolates of Burkholderia pseudomallei from Thailand.
• Public awareness of melioidosis in Thailand and potential use of video clips as educational tools.
• Mortality Attributable to Seasonal Influenza A and B Infections in Thailand, 2005--2009: A Longitudinal Study
• Paragonimiasis as an Important Alternative Misdiagnosed Disease for Suspected Acid-fast Bacilli Sputum Smear-Negative Tuberculosis Response
• Systematic review and consensus guidelines for environmental sampling of Burkholderia pseudomallei
• Estimating the true accuracy of diagnostic tests for dengue infection using bayesian latent class models
• Microevolution of Burkholderia pseudomallei during an acute infection
• Burkholderia pseudomallei in Water Supplies, Southern Thailand
• Increasing incidence of hospital-acquired and healthcare-associated bacteremia in northeast Thailand: a multicenter surveillance study
• Failure of Burkholderia pseudomallei to Grow in an Automated Blood Culture System
• Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis
• Maintenance of Leptospira Species in Leptospira Vanaporn Wuthiekanun Agar
• Activities of daily living associated with acquisition of melioidosis in northeast Thailand: a matched case-control study
• Host responses to melioidosis and tuberculosis are both dominated by interferon-mediated signaling
• A qualitative exploration into infection control practices and obstacles to improvements amongst health care workers at a regional hospital
• Long-term survival after intensive care unit discharge in Thailand: a retrospective study
• Rapid isolation and susceptibility testing of Leptospira spp. using a new solid medium, LVW agar
• The epidemiology of pediatric bone and joint infections in Cambodia, 2007--11
• Monoclonal antibody-based immunofluorescence microscopy for the rapid identification of Burkholderia pseudomallei in clinical specimens
• Correction: Melioidosis Vaccines: A Systematic Review and Appraisal of the Potential to Exploit Biodefense Vaccines for Public Health Purposes
• The value of intermittent point-prevalence surveys of healthcare-associated infections for evaluating infection control interventions at Angkor Hospital for Children, Siem Reap, Cambodia
• Leptospira species in floodwater during the 2011 floods in the Bangkok Metropolitan Region, Thailand
• Clinical definitions of melioidosis
• Correction: Epidemiology, Microbiology and Mortality Associated with Community-Acquired Bacteremia in Northeast Thailand: A Multicenter Surveillance Study
• Prevalence of melioidosis in patients with suspected pulmonary tuberculosis and sputum smear negative for acid-fast bacilli in northeast Thailand
• Rapid detection of Burkholderia pseudomallei in blood cultures using a monoclonal antibody-based immunofluorescent assay
• Melioidosis caused by Burkholderia pseudomallei in drinking water, Thailand, 2012
• Determinants of mortality in a combined cohort of 501 patients with HIV-associated cryptococcal meningitis: implications for improving outcomes
• The role of NOD2 in murine and human melioidosis
• Trimethoprim-sulfamethoxazole versus trimethoprim-sulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): a multicentre, double-blind, non-inferiority, randomised controlled trial
• Role of Burkholderia pseudomallei biofilm formation and lipopolysaccharide in relapse of melioidosis
• Zero tolerance for healthcare-associated MRSA bacteraemia: is it realistic?
• Environmental presence of Burkholderia pseudomallei in rice fields as determined by direct PCR from soil samples
• Fatal melioidosis in goats in Bangkok, Thailand
• Melioidosis Diagnostic Workshop, 2013
• Maintenance of Leptospira spp. in LVW agar
• Melioidosis in Africa: should we be looking more closely?
• New Insights from the 7th World Melioidosis Congress 2013
• Burkholderia pseudomallei is spatially distributed in soil in northeast Thailand
• Patterns of organ involvement in recurrent melioidosis
• Gamma interferon supplementation for melioidosis
• Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian latent class models
• Enzyme-linked immunosorbent assay for the diagnosis of melioidosis: better than we thought
• Within-host evolution of Burkholderia pseudomallei in four cases of acute melioidosis
• i 1 August News iii In the Literature v Crossing Borders: One World, Global Health
• Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis
• Fool's gold: Why imperfect reference tests are undermining the evaluation of novel diagnostics: a reevaluation of 5 diagnostic tests for leptospirosis
• Burkholderia pseudomallei is genetically diverse in agricultural land in Northeast Thailand
• Effect of colony morphology variation of Burkholderia pseudomallei on intracellular survival and resistance to antimicrobial environments in human macrophages in vitro
• Accuracy of a commercial IgM ELISA for the diagnosis of human leptospirosis in Thailand
• Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand
• Toll-Like Receptor Pathway Gene Variants And Susceptibility To Melioidosis
• Proteomic analysis of colony morphology variants of Burkholderia pseudomallei defines a role for the arginine deiminase system in bacterial survival
• Molecular detection and speciation of pathogenic Leptospira spp. in blood from patients with culture-negative leptospirosis
• Increasing incidence of human melioidosis in Northeast Thailand
• Independent association between rate of clearance of infection and clinical outcome of HIV-associated cryptococcal meningitis: analysis of a combined cohort of 262 patients
• Melioidosis in animals, Thailand, 2006--2010
• Repeat blood culture positive for B. pseudomallei indicates an increased risk of death from melioidosis
• Pathogenicity of high-dose enteral inoculation of Burkholderia pseudomallei to mice
• Animal melioidosis in Thailand
• Defining the true accuracy of diagnostic tests when the gold standard is imperfect using web-based application
• Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010
• Development and validation of Burkholderia pseudomallei-specific real-time PCR assays for clinical, environmental or forensic detection applications
• Melioidosis: a clinical overview
• Diagnostic accuracy of real-time PCR assays targeting 16S rRNA and lipL32 genes for human leptospirosis in Thailand: a case-control study
• Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei
• Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei
• Human immune responses to Burkholderia pseudomallei characterized by protein microarray analysis
• Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis
• Survey of antimicrobial resistance in clinical B. pseudomallei isolates over two decades in northeast Thailand
• Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes
• Development of ceftazidime resistance in an acute Burkholderia pseudomallei infection
• Long-term outcome of Q fever endocarditis
• Highly sensitive direct detection and quantification of Burkholderia pseudomallei bacteria in environmental soil samples by using real-time PCR
• Feasibility of modified surviving sepsis campaign guidelines in a resource-restricted setting based on a cohort study of severe S. aureus sepsis
• Effectiveness of a Simplified Method for Isolation of Burkholderia pseudomallei from Soil
• Improved culture-based detection and quantification of Burkholderia pseudomallei from soil
• Rate of clearance of infection is independently associated with clinical outcome in HIV-associated cryptococcal meningitis: analysis of a combined cohort of 262 patients
• Accuracy of loop-mediated isothermal amplification for diagnosis of human leptospirosis in Thailand
• Excess length of stay due to hospital-associated infections in Thailand: 8 years retrospective data
• A retrospective study to define the incidence and associated mortality of hospital-acquired bacteraemia at a regional hospital in northeast Thailand
• Correction: Diagnostic Accuracy of Real-Time PCR Assays Targeting 16S rRNA and lipl32 Genes for Human Leptospirosis in Thailand: A Case-Control Study
• Lack of correlation of Burkholderia pseudomallei quantities in blood, urine, sputum and pus
• Epidemiology, microbiology and mortality of community-acquired bacteremia in northeast Thailand: a multicenter population-based study
• Correction: Feasibility of Modified Surviving Sepsis Campaign Guidelines in a Resource-Restricted Setting Based on a Cohort Study of Severe S. Aureus Sepsis.
• Pediatric Suppurative Parotitis in Cambodia 2007-2011
• Identification of differentially expressed proteins from Burkholderia pseudomallei isolated during primary and relapsing melioidosis
• Europe PMC Funders Group
• Burkholderia pseudomallei genome plasticity associated with genomic island variation
• A randomized controlled trial of granulocyte colony-stimulating factor for the treatment of severe sepsis due to melioidosis in Thailand
• Trimethoprim/sulfamethoxazole resistance in clinical isolates of Burkholderia pseudomallei
• MICE: An open-access tool for accuracy estimates of diagnostic tests in absence of a gold standard
• ARTICLES AND COMMENTARIES-A Randomized Controlled Trial of Granulocyte Colony-Stimulating Factor for the Treatment of Severe Sepsis Due to Melioidosis in Thailand
• Variable presentation of neurological melioidosis in Northeast Thailand
• Prospective clinical evaluation of the accuracy of 16S rRNA real-time PCR assay for the diagnosis of melioidosis
• turning green with shock
• Biological relevance of colony morphology and phenotypic switching by Burkholderia pseudomallei
• Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidosis
• Two randomized controlled trials of ceftazidime alone versus ceftazidime in combination with trimethoprim-sulfamethoxazole for the treatment of severe melioidosis
• Direct in vivo assessment of microcirculatory dysfunction in severe falciparum malaria
• Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)
• Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents
• Role and significance of quantitative urine cultures in diagnosis of melioidosis
• Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis
• Efforts to Enhance Detection of Burkholderia pseudomallei Among Young Children with Severe Pneumonia
• Melioidosis, 2011-Thailand: drinking water source
• Rapid immunofluorescence microscopy for diagnosis of melioidosis
• Risk factors for recurrent melioidosis in northeast Thailand
• Genetic diversity and microevolution of Burkholderia pseudomallei in the environment
• An addition to the effect of treating co-infections on HIV-1 viral load
• Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance
• Prospective evaluation of a rapid immunochromogenic cassette test for the diagnosis of melioidosis in northeast Thailand
• Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis
• Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures
• High-throughput mRNA profiling characterizes the expression of inflammatory molecules in sepsis caused by Burkholderia pseudomallei
• Strategies to reduce mortality from bacterial sepsis in adults in developing countries
• Optimization of culture of Leptospira from humans with leptospirosis
• Antibodies from patients with melioidosis recognize Burkholderia mallei but not Burkholderia thailandensis antigens in the indirect hemagglutination assay
• Quantitation of B. pseudomallei in clinical samples
• Simultaneous infection with more than one strain of Burkholderia pseudomallei is uncommon in human melioidosis
• Loop-mediated isothermal amplification method targeting the TTS1 gene cluster for detection of Burkholderia pseudomallei and diagnosis of melioidosis
• A simple scoring system to differentiate between relapse and re-infection in patients with recurrent melioidosis
• Invasive Erysipelothrix rhusiopathiae infection in northeast Thailand.
• Intensity of exposure and incidence of melioidosis in Thai children
• Rheumatological manifestations in patients with melioidosis.
• Determinants of recurrent melioidosis
• Toll-Like Receptor Pathway Gene Variants And Susceptibility To Melioidosis
• Automating the Generation of Antimicrobial Resistance Surveillance Reports: Proof-of-Concept Study Involving Seven Hospitals in Seven Countries.
• Sensitivity and specificity of DPP® Fever Panel II Asia in the diagnosis of malaria, dengue and melioidosis
• Identifying context-specific domains for assessing antimicrobial stewardship programmes in Asia: protocol for a scoping review
• Impact of a multimodal hand hygiene improvement intervention in a 1000-bed hospital in Thailand: a stepped wedge cluster randomized controlled trial
• External validation and updating of clinical severity scores to guide referral of young children with acute respiratory infections in resource-limited primary care settings
• Defining the role of host biomarkers in the diagnosis and prognosis of childhood pneumonia – a prospective cohort study
• Use of antimicrobials during the COVID-19 pandemic: a qualitative study among stakeholders in Nepal
• Local and timely antimicrobial resistance data for local and national actions: the early implementation of an automated tool for data analysis at local hospital level in Thailand
• BurkHostGEN: a study protocol for evaluating variations in the Burkholderia pseudomallei and host genomes associated with melioidosis infection [version 1; peer review: awaiting peer review]
• Burkholderia pseudomallei and melioidosis.
• Defining the role of host biomarkers in the diagnosis and prognosis of the severity of childhood pneumonia: a prospective cohort study.
• IL-1R2-based biomarker models predict melioidosis mortality independent of clinical data.
• Raising awareness of antimicrobial resistance: development of an 'antibiotic footprint calculator'.
• Excess mortality attributable to antimicrobial-resistant bacterial bloodstream infection at a tertiary-care hospital in Indonesia.
• EPI-Net One Health reporting guideline for antimicrobial consumption and resistance surveillance data: a Delphi approach.
• Excess Mortality Attributable to Hospital-Acquired Antimicrobial-Resistant Infections: A 2-Year Prospective Surveillance Study in Northeast Thailand.
• Comparative clinical characteristics and outcomes of patients with community acquired bacteremia caused by Escherichia coli, Burkholderia pseudomallei and Staphylococcus aureus: A prospective observational study (Ubon-sepsis).
• Effect of Delays in Concordant Antibiotic Treatment on Mortality in Patients With Hospital-Acquired Acinetobacter Species Bacteremia: Emulating a Target Randomized Trial With a 13-Year Retrospective Cohort.
• Blood culture utilization and epidemiology of antimicrobial-resistant bloodstream infections before and during the COVID-19 pandemic in the Indonesian national referral hospital.
• Epidemiology of Extended-Spectrum Beta-Lactamase and Carbapenemase-Producing Enterobacterales in the Greater Mekong Subregion: A Systematic-Review and Meta-Analysis of Risk Factors Associated With Extended-Spectrum Beta-Lactamase and Carbapenemase Isolation.
• Surveillance strategies using routine microbiology for antimicrobial resistance in low- and middle-income countries.
• Reducing antibiotic treatment duration for ventilator-associated pneumonia (REGARD-VAP): a trial protocol for a randomised clinical trial.
• Effectiveness of a sepsis programme in a resource-limited setting: a retrospective analysis of data of a prospective observational study (Ubon-sepsis).
• Antibiotic knowledge, attitudes and practices: new insights from cross-sectional rural health behaviour surveys in low-income and middle-income South-East Asia.
• A call to action: time to recognise melioidosis as a neglected tropical disease.
• Evaluation of antigen-detecting and antibody-detecting diagnostic test combinations for diagnosing melioidosis.
• Role of Burkholderia pseudomallei-Specific IgG2 in Adults with Acute Melioidosis, Thailand.
• Co-evolutionary Signals Identify Burkholderia pseudomallei Survival Strategies in a Hostile Environment.
• A multi-country study using MALDI-TOF mass spectrometry for rapid identification of Burkholderia pseudomallei.
• Interpreting Burkholderia pseudomallei disc diffusion susceptibility test results by the EUCAST method.
• Impact of low blood culture usage on rates of antimicrobial resistance.
• A 2-Biomarker Model Augments Clinical Prediction of Mortality in Melioidosis.
• Utility of qSOFA and modified SOFA in severe malaria presenting as sepsis.
• Improved characterisation of MRSA transmission using within-host bacterial sequence diversity.
• Global burden of melioidosis in 2015: a systematic review and data synthesis.
• Clinical Epidemiology of 7126 Melioidosis Patients in Thailand and the Implications for a National Notifiable Diseases Surveillance System.
• The Lancet Infectious Diseases Commission on antimicrobial resistance: 6 years later.
• Early management of sepsis in medical patients in rural Thailand: a single-center prospective observational study.
• Improving the estimation of the global burden of antimicrobial resistant infections.
• Evaluation of consensus method for the culture of Burkholderia pseudomallei in soil samples from Laos.
• Diabetes alters immune response patterns to acute melioidosis in humans.
• The global impact and cost-effectiveness of a melioidosis vaccine.
• Viruses in Vietnamese Patients Presenting with Community-Acquired Sepsis of Unknown Cause.
• 'Antibiotic footprint' as a communication tool to aid reduction of antibiotic consumption.
• Antimicrobial-resistant Gram-negative colonization in infants from a neonatal intensive care unit in Thailand.
• Microbiology Investigation Criteria for Reporting Objectively (MICRO): a framework for the reporting and interpretation of clinical microbiology data.
• Detection of vancomycin-resistant Enterococcus faecium hospital-adapted lineages in municipal wastewater treatment plants indicates widespread distribution and release into the environment.
• Detection and Characterization of Human Pegivirus 2, Vietnam.
• Effect of point-of-care C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in Thailand and Myanmar: an open-label, randomised, controlled trial.
• Antibodies in Melioidosis: The Role of the Indirect Hemagglutination Assay in Evaluating Patients and Exposed Populations.
• Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis.
• Harnessing alternative sources of antimicrobial resistance data to support surveillance in low-resource settings.
• Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis).
• Cost-effectiveness of interventions to improve hand hygiene in healthcare workers in middle-income hospital settings: a model-based analysis.
• Misidentification of Burkholderia pseudomallei as Acinetobacter species in northern Thailand.
• Global Burden and Challenges of Melioidosis.
• Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries.
• The global burden of sepsis: barriers and potential solutions.
• Melioidosis in Thailand: Present and Future.
• Duration of exposure to multiple antibiotics is associated with increased risk of VRE bacteraemia: a nested case-control study.
• Antibiotic use in poultry: a survey of eight farms in Thailand.
• Embedding community and public voices in co-created solutions to mitigate antimicrobial resistance (AMR) in Thailand using the ′Responsive Dialogues′ public engagement framework
• Plasma Metabolomics Reveals Distinct Biological and Diagnostic Signatures for Melioidosis
• Prognostic accuracy of screening tools for clinical deterioration in adults with suspected sepsis in northeastern Thailand: a cohort validation study
• Diabetes mellitus is associated with a shared hyper-inflammatory immune response in melioidosis and tuberculosis patients: an observational case-control study
• Prevalence of Extended-spectrum ß-lactamase (ESBL)-producing Enterobacterales in edible ice in Thailand
• Enhanced bedside mortality prediction combining point-of-care lactate and the quick Sequential Organ Failure Assessment (qSOFA) score in patients hospitalised with suspected infection in southeast Asia: a cohort study.
• External validation of clinical severity scores to guide referral of paediatric acute respiratory infections in resource-limited primary care settings
• Epidemiology of Burkholderia pseudomallei, Streptococcus suis, Salmonella spp., Shigella spp. and Vibrio spp. infections in 111 hospitals in Thailand, 2022
• Antimicrobial resistance and the great divide: inequity in priorities and agendas between the Global North and the Global South threatens global mitigation of antimicrobial resistance
• Use of antimicrobials during the COVID-19 pandemic: A qualitative study among stakeholders in Nepal
• Barriers and enablers to blood culture sampling: a systematic review and theoretical domains framework survey in Indonesia, Thailand and Vietnam
• Embedding community and public voices in co-created solutions to mitigate antimicrobial resistance (AMR) in Thailand using the ‘Responsive Dialogues’ public engagement framework
• Higher Frequency and Mortality Rate of Antimicrobial-resistant Bloodstream Infections in Tertiary-care Hospitals Compared with Secondary-care Hospitals in Thailand
• Frequency and mortality rate following antimicrobial-resistant bloodstream infections in tertiary-care hospitals compared with secondary-care hospitals
• Use of antimicrobials during the COVID-19 pandemic: A qualitative study among stakeholders in Nepal
• Barriers and enablers to blood culture sampling in Indonesia, Thailand and Viet Nam: a Theoretical Domains Framework-based survey
• Individualised, short-course antibiotic treatment versus usual long-course treatment for ventilator-associated pneumonia (REGARD-VAP): a multicentre, individually randomised, open-label, non-inferiority trial
• The anthropogenic fingerprint on emerging infectious diseases
• Identifying context-specific domains for assessing antimicrobial stewardship programmes in Asia: Protocol for a scoping review
• Automating the Generation of Notifiable Bacterial Disease Reports: Proof-of-Concept Study and Implementation in Six Hospitals in Thailand
• Dysregulated immunologic landscape of the early host response in melioidosis
• Erratum: Correction: Clinical epidemiology and outcomes of community acquired infection and sepsis among hospitalized patients in a resource limited setting in Northeast Thailand: A prospective observational study (Ubon-sepsis) (PloS one (2018) 13 9 (e0204509))
• Embedding community and public voices in co-created solutions to mitigate antimicrobial resistance (AMR) in Thailand using the ‘Responsive Dialogues’ public engagement framework
• Reducing Antibiotic Treatment Duration for Ventilator-Associated Pneumonia - A Multicentre, Individually-Randomised, Open-Label, Non-Inferiority Trial (REGARD-VAP)
• Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
• Identification of Burkholderia cepacia strains that express a Burkholderia pseudomallei-like capsular polysaccharide
• Frequency of antimicrobial-resistant bloodstream infections in Thailand, 2022
• Pneumonia-Specific Plasma Metabolite Profiles Among Patients Hospitalized with Infection in Southeast Asia
• Diagnostic and antibiotic use practices among COVID-19 and non-COVID-19 patients in the Indonesian National Referral Hospital
• WHO global research priorities for antimicrobial resistance in human health
• A nationwide mixed-methods study of gaps and barriers to implementation of antimicrobial stewardship programmes in hospitals in Indonesia
• 'AMR Dialogues': A public engagement initiative to shape policies and solutions on antimicrobial resistance (AMR) in Thailand
• Frequency of antimicrobial-resistant bloodstream infections in 111 hospitals in Thailand, 2022
• Melioidosis in Patients with COVID-19 Exposed to Contaminated Tap Water, Thailand, 2021
• Prognostic Accuracy of Screening Tools for Clinical Deterioration in Adults With Suspected Sepsis in Northeastern Thailand: A Cohort Validation Study
• BurkHostGEN: a study protocol for evaluating variations in the Burkholderia pseudomallei and host genomes associated with melioidosis infection
• 'Antibiotic footprint' as a communication tool to aid reduction of antibiotic consumption-authors' response
• Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei
• Effect of delays in concordant antibiotic treatment on mortality in patients with hospital-acquired Acinetobacter spp. bacteremia: A 13-year retrospective cohort
• Co-evolutionary signals from Burkholderia pseudomallei population genomics highlight its survival strategy in a hostile environment
• Associations between Wearing Masks, Washing Hands, and Social Distancing Practices, and Risk of COVID-19 Infection in Public: A Cohort-Based Case-Control Study in Thailand
• Associations between mask-wearing, handwashing, and social distancing practices and risk of COVID-19 infection in public: a case-control study in Thailand
• Leapfrogging laboratories: The promise and pitfalls of high-tech solutions for antimicrobial resistance surveillance in low-income settings
• Automating the generation of antimicrobial resistance surveillance reports: A proof-of-concept study in seven hospitals in seven countries
• Antimicrobial Resistance in the Asia Pacific region: A meeting report
• Recommendations for the Prevention of Melioidosis
• Development of enzyme-linked immunosorbent assay for human leptospirosis serodiagnosis using leptospira secretome antigen
• Evolution of the Staphylococcus argenteus ST2250 clone in Northeastern Thailand is linked with the acquisition of livestock-associated staphylococcal genes
• Melioidosis
• A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis
• A current perspective on antimicrobial resistance in Southeast Asia
• Susceptibility of clinical isolates of burkholderia pseudomallei to a lipid a biosynthesis inhibitor
• Gastrointestinal tract involvement in melioidosis
• Clinical epidemiology of septic arthritis caused by Burkholderia pseudomallei and other bacterial pathogens in Northeast Thailand
• Presence of B. thailandensis and B. thailandensis expressing B. pseudomallei-like capsular polysaccharide in Thailand, and their associations with serological response to B. pseudomallei
• Presence of Burkholderia pseudomallei in soil and paddy rice water in a rice field in Northeast Thailand, but not in air and rainwater
• What’s wrong in the control of antimicrobial resistance in critically ill patients from low- and middle-income countries?
• Infection with Burkholderia pseudomallei-immune correlates of survival in acute melioidosis
• Capacity and utilization of blood culture in two referral hospitals in Indonesia and Thailand
• A comparison of two molecular methods for diagnosing leptospirosis from three different sample types in patients presenting with fever in Laos
• Commentary: data sharing in South East Asia
• Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC): Supporting the transition from strategy to action
• Comparison of two chromogenic media for the detection of vancomycin-resistant enterococcal carriage by nursing home residents
• Global and regional dissemination and evolution of Burkholderia pseudomallei
• A retrospective analysis of melioidosis in Cambodian children, 2009-2013
• Association between activities related to routes of infection and clinical manifestations of melioidosis
• Melioidosis: The hazards of incomplete peer-review
• A rapid immunochromatography test based on Hcp1 is a potential point-of-care test for serological diagnosis of melioidosis
• Multitarget quantitative PCR improves detection and predicts cultivability of the pathogen Burkholderia pseudomallei
• Comparison of 2 chromogenic media for the detection of extended-spectrum β-lactamase producing Enterobacteriaceae stool carriage in nursing home residents
• Causes and outcomes of sepsis in southeast Asia: a multinational multicentre cross-sectional study
• Rapid design and fielding of four diagnostic technologies in Sierra Leone, Thailand, Peru, and Australia: Successes and challenges faced introducing these biosensors
• Antibiotics and activity spaces: Protocol of an exploratory study of behaviour, marginalisation and knowledge diffusion
• Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for the identification of Burkholderia pseudomallei from Asia and Australia and differentiation between Burkholderia species
• Development of rapid enzyme-linked immunosorbent assays for detection of antibodies to Burkholderia pseudomallei
• Burkholderia pseudomallei: Challenges for the clinical microbiology laboratory-A response from the front line
• Human infection with Burkholderia thailandensis, China, 2013
• Utility of SOFA score, management and outcomes of sepsis in Southeast Asia: A multinational multicenter prospective observational study
• Activities of Daily Living Associated with Acquisition of Melioidosis in Northeast Thailand: A Matched Case-Control Study
• Utility of a Lateral Flow Immunoassay (LFI) to Detect Burkholderia pseudomallei in Soil Samples
• Increasing incidence of hospital-acquired and healthcare-associated bacteremia in northeast Thailand: A multicenter surveillance study
• Mortality attributable to seasonal influenza A and B infections in Thailand, 2005-2009: A longitudinal study
• Optimal cutoff and accuracy of an IgM Enzyme-Linked immunosorbent assay for diagnosis of acute scrub typhus in Northern Thailand: An alternative reference method to the IgM immunofluorescence assay
• How to determine the accuracy of an alternative diagnostic test when it is actually better than the reference tests: A re-evaluation of diagnostic tests for scrub typhus using Bayesian LCMs
• Consensus on the development of vaccines against naturally acquired melioidosis
• Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis
• Public awareness of Melioidosis in Thailand and potential use of video clips as educational tools
• NLRC4 and TLR5 Each Contribute to Host Defense in Respiratory Melioidosis
• Evaluation of polysaccharide-based latex agglutination assays for the rapid detection of antibodies to burkholderia pseudomallei
• Erratum to Cost-effectiveness analysis of parenteral antimicrobials for acute melioidosis in Thailand [Trans R Soc Trop Med Hyg, 109, (2015), 416-418]
• Toxicity of amphotericin B deoxycholate-based induction therapy in patients with HIV-associated cryptococcal meningitis
• Comparative efficacy of interventions to promote hand hygiene in hospital: Systematic review and network meta-analysis
• Extended loop region of Hcp1 is critical for the assembly and function of type VI secretion system in Burkholderia pseudomallei
• Burkholderia pseudomallei in water supplies, Southern Thailand
• In response
• Development of a Prototype Lateral Flow Immunoassay (LFI) for the Rapid Diagnosis of Melioidosis
• Estimating the True Accuracy of Diagnostic Tests for Dengue Infection Using Bayesian Latent Class Models
• Melioidosis in Africa: Should we be looking more closely?
• Quality controls for antimicrobial disk diffusion testing on Leptospira Vanaporn Wuthiekanun agar
• Short report: Fatal melioidosis in goats in Bangkok, Thailand
• Zero tolerance for healthcare-associated MRSA bacteraemia: Is it realistic?
• Soil nutrient depletion is associated with the presence of Burkholderia pseudomallei
• New insights from the 7th world melioidosis congress 2013
• Determinants of mortality in a combined cohort of 501 patients with HIV-associated cryptococcal meningitis: Implications for improving outcomes
• Short Report: Failure of Burkholderia pseudomallei to Grow in an Automated Blood Culture System
• Optimal cutoff titers for indirect immunofluorescence assay for diagnosis of scrub typhus
• Short report: Evaluation of a latex agglutination assay for the identification of Burkholderia pseudomallei and Burkholderia mallei
• The effects of signal erosion and core genome reduction on the identification of diagnostic markers
• Clinical, environmental, and serologic surveillance studies of melioidosis in gabon, 2012–2013
• T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients
• Emergence of melioidosis in Indonesia
• Maintenance of Leptospira species in Leptospira Vanaporn Wuthiekanun agar
• Role of burkholderia pseudomallei biofilm formation and lipopolysaccharide in relapse of melioidosis
• Impact of routine bedside infectious disease consultation on clinical management and outcome of Staphylococcus aureus bacteraemia in adults
• Antimicrobial disk susceptibility testing of leptospira spp. Using leptospira vanaporn wuthiekanun (LVW) agar
• Epidemiology, Microbiology and Mortality Associated with Community-Acquired Bacteremia in Northeast Thailand: A Multicenter Surveillance Study
• Trimethoprim/sulfamethoxazole resistance in clinical isolates of Burkholderia pseudomallei from Thailand
• Trimethoprim-sulfamethoxazole versus trimethoprimsulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): A multicentre, double-blind, non-inferiority, randomised controlled trial
• Erratum: Melioidosis in Africa: Should we be looking more closely? (Future Microbiology (2015) 10:2 (273-281))
• Short report: Repeat blood culture positive for B. pseudomallei indicates an increased risk of death from melioidosis
• Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010
• Burkholderia pseudomallei is spatially distributed in soil in Northeast Thailand
• Short report: Rapid detection of Burkholderia pseudomallei in blood cultures using a monoclonal antibody-based immunofluorescent assay
• Enzyme-linked immunosorbent assay for the diagnosis of melioidosis: Better than we thought
• Melioidosis in animals, Thailand, 2006-2010
• Long-term survival after intensive care unit discharge in Thailand: A retrospective study
• Development of ceftazidime resistance in an acute burkholderia pseudomallei infection
• Increasing incidence of human melioidosis in northeast Thailand
• Rapid isolation and susceptibility testing of Leptospira spp. Using a new solid medium, LVW agar
• Short report: Leptospira species in floodwater during the 2011 floods in the bangkok metropolitan region, Thailand
• The value of intermittent point-prevalence surveys ofhealthcare-associated infections fo evaluating infection control interventions at angkor hospital for children, siem reap, cambodia
• Melioidosis vaccines: A systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes
• The epidemiology of pediatric bone and joint infections in cambodia, 2007-11
• Systematic Review and Consensus Guidelines for Environmental Sampling of Burkholderia pseudomallei
• Feasibility of modified surviving sepsis campaign guidelines in a resource-restricted setting based on a cohort study of severe s. aureus sepsis
• Short report: Monoclonal antibody-based immunofluorescence microscopy for the rapid identification of burkholderia pseudomallei in clinical specimens
• Subpopulations of Staphylococcus aureus Clonal Complex 121 Are Associated with Distinct Clinical Entities
• Short report: Prevalence of melioidosis in patients with suspected pulmonary tuberculosis and sputum smear negative for acid-fast bacilli in northeast Thailand
• Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand
• Effectiveness of a simplified method for isolation of Burkholderia pseudomallei from soil
• Pediatric suppurative parotitis in cambodia between 2007 and 2011
• Burkholderia pseudomallei is genetically diverse in agricultural land in northeast Thailand
• Melioidosis: A clinical overview
• Diagnostic accuracy of real-time PCR assays targeting 16S rRNA and lipl32 genes for human leptospirosis in Thailand: A case-control study
• Short report: Molecular confirmation of co-infection by pathogenic leptospira spp. and orientia tsutsugamushi in patients with acute febrile illness in Thailand
• Diabetes does not influence activation of coagulation, fibrinolysis or anticoagulant pathways in Gram-negative sepsis (melioidosis)
• Host Responses to Melioidosis and Tuberculosis Are Both Dominated by Interferon-Mediated Signaling
• Development and validation of burkholderia pseudomallei-specific real-time pcr assays for clinical, environmental or forensic detection applications
• Fool's gold: Why imperfect reference tests are undermining the evaluation of novel diagnostics: A reevaluation of 5 diagnostic tests for leptospirosis
• Turning green with shock
• Lack of correlation of burkholderia pseudomallei quantities in blood, urine, sputum and pus
• Rheumatological manifestations in patients with melioidosis
• Invasive erysipelothrix rhusiopathiae infection in Northeast Thailand
• Independent association between rate of clearance of infection and clinical outcome of hiv-associated cryptococcal meningitis: Analysis of a combined cohort of 262 patients
• Short report: Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis
• Variable presentation of neurological melioidosis in northeast Thailand
• Short report: Patterns of organ involvement in recurrent melioidosis
• Short report: Quantitation of B. pseudomallei in clinical samples
• Staphylococcus aureus bacteraemia in a tropical setting: Patient outcome and impact of antibiotic resistance
• Insights of SEDRIC, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium [version 1; peer review: awaiting peer review]