Daniel Gao

Publications

• In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration
• Adenine Base Editing in vivo with a Single Adeno-Associated Virus Vector
• Co-regulation of alternative splicing by hnRNPM and ESRP1 during EMT.
• Prime editing: current advances and therapeutic opportunities in human diseases
• Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing
• Phage-assisted evolution and protein engineering yield compact, efficient prime editors
• Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing
• Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing
• C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2.
• Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins
• NmeCas9 is an intrinsically high-fidelity genome-editing platform
• Adapting dCas9-APEX2 for subnuclear proteomic profiling
• CD44 splice isoform switching determines breast cancer stem cell state
• Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII Expression in Recessive Dystrophic Epidermolysis Bullosa
• Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome
• In vivo prime editing rescues photoreceptor degeneration in nonsense mutant retinitis pigmentosa