Binsheng Gong

Publications

• Ultra-deep sequencing data from a liquid biopsy proficiency study demonstrating analytic validity
• Ultra-deep multi-oncopanel sequencing of benchmarking samples with a wide range of variant allele frequencies
• Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
• A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency
• Assessment of Clonal Expansion Using CarcSeq Measurement of Lung Cancer Driver Mutations and Correlation With Mouse Strain- and Sex-Related Incidence of Spontaneous Lung Neoplasia
• Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions
• Identification of Translational microRNA Biomarker Candidates for Ketoconazole-Induced Liver Injury Using Next-Generation Sequencing
• Impact of Sequencing Depth and Library Preparation on Toxicological Interpretation of RNA-Seq Data in a “Three-Sample” Scenario
• A robust approach based on Weibull distribution for clustering gene expression data
• A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium
• The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance
• Characterization of microRNA Expression Patterns and their Target Genes to Discover Potential Biomarkers for Hepatacaciongenesis after Exposed to Thioacetamide in Rats
• An investigation of biomarkers derived from legacy microarray data for their utility in the RNA-seq era
• Bioinformatics Applications Reveal Gene Regulation Complexities in Response to Toxicant Exposures
• Discovering Functional Modules by Topic Modeling RNA-Seq Based Toxicogenomic Data
• Global gene expression distribution in non-cancerous complex diseases
• Genetic control of primary microRNA insight into cis- and trans-regulatory variations by RNA-seq
• Combined gene expression and protein interaction analysis of dynamic modularity in glioma prognosis
• Disease-driven detection of differential inherited SNP modules from SNP network
• DOSim: An R package for similarity between diseases based on Disease Ontology
• Functional Homogeneity in microRNA Target Heterogeneity-a New Sight into Human microRNomics
• Disease embryo development network reveals the relationship between disease genes and embryo development genes
• From phenotype to gene: Detecting disease-specific gene functional modules via a text-based human disease phenotype network construction
• Novel strategies to mine alcoholism-related haplotypes and genes by combining existing knowledge framework
• MicroRNA regulation constrains the organization of target genes on mammalian chromosomes
• SubpathwayMiner: a software package for flexible identification of pathways
• Application of a genetic algorithm - Support vector machine hybrid for prediction of clinical phenotypes based on genome-wide SNP profiles of Sib pairs
• Gene mining: a novel and powerful ensemble decision approach to hunting for disease genes using microarray expression profiling
• A systematic method for mapping multiple loci: An application to construct a genetic network for rheumatoid arthritis
• Correlation between genetic polymorphism of cytokine genes, plasma protein levels and bronchial asthma in the Han people in northern China
• Role of coxsackievirus and adenovirus receptor in the pathogenesis of dilated cardiomyopathy and its influencing factor
• Data mining of RNA expression and DNA genotype data: Presentation group 5 contributions to Genetic Analysis Workshop 15
• Familial aggregation analysis of gene expressions.
• Single-nucleotide polymorphism-gene intermixed networking reveals co-linkers connected to multiple gene expression phenotypes.
• Novel strategies to identify relevant molecular signatures for complex human diseases based on data of identical-by-decent profiles and genomic context.
• Analysis of sib-pair IBD profiles and genomic context for identification of the relevant molecular signatures for alcoholism
• Multivariate sib-pair linkage analysis of longitudinal phenotypes by three step-wise analysis approaches
• Landscape of circRNAs Across 11 Organs and 4 Ages in Fischer 344 Rats