Benjamin Tam

Publications

• Ethnic‐specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population
• Identification of deleterious variants of uncertain significance in BRCA2 BRC4 repeat through molecular dynamics simulations
• Evolutionary Origin of Germline Pathogenic MUTYH Variations in Modern Humans
• Applications of Molecular Dynamics Simulation in Protein Study
• Short Naphthalene Organophosphonate Linkers to Microporous Frameworks
• ZnO@ZIF-8: Gas sensitive core-shell hetero-structures show reduced cross-sensitivity to humidity
• Prevalence and spectrum of DNA mismatch repair gene variation in the general Chinese population
• Design of electric field controlled molecular gates mounted on metal–organic frameworks
• From 2-methylimidazole to 1,2,3-triazole: a topological transformation of ZIF-8 and ZIF-67 by post-synthetic modification
• Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model
• RBD Double Mutations of SARS-CoV-2 Strains Increase Transmissibility through Enhanced Interaction between RBD and ACE2 Receptor
• Comprehensive Identification of Deleterious TP53 Missense VUS Variants Based on Their Impact on TP53 Structural Stability
• Classification of PTEN missense VUS through exascale simulations
• Short Naphthalene Organophosphonate Linkers to Microporous Frameworks
• From 2-methylimidazole to 1,2,3-triazole: a topological transformation of ZIF-8 and ZIF-67 by post-synthetic modification
• ZnO@ZIF-8: Gas sensitive core-shell hetero-structures show reduced cross-sensitivity to humidity
• TP53 germline pathogenic variants in modern humans were likely originated during recent human history
• Integration of deep learning with Ramachandran plot molecular dynamics simulation for genetic variant classification
• DARVIC Dihedral angle-reliant variant impact classifier for functional prediction of missense VUS
• Design of electric field controlled molecular gates mounted on metal-organic frameworks
• Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model
• Classification of MLH1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method