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Alessandro Bartolomucci

Publications

  • Social determinants of health and survival in humans and other animals
  • Psychosocial Risk Factors, Noncommunicable Diseases, and Animal Models for COVID-19
  • Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice
  • The molecular identity of the TLQP-21 peptide receptor
  • Correction: The molecular identity of the TLQP-21 peptide receptor
  • Contextual modifiers of healthspan, lifespan, and epigenome in mice under chronic social stress
  • The impact of life stress on hallmarks of aging and accelerated senescence: Connections in sickness and in health
  • Making Sense of the Costs of Adversity Throughout the Lifespan on Aging in Humans and Other Animals
  • The fortunes and misfortunes of social life across the life course: A new era of research from field, laboratory and comparative studies
  • The mouse Social Frailty Index (mSFI): a novel behavioral assessment for impaired social functioning in aging mice
  • Functional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism
  • Conditional inactivation of limbic neuropeptide y-1 receptors increases vulnerability to diet-induced obesity in male mice
  • The VGF-derived peptide TLQP-62 modulates insulin secretion and glucose homeostasis
  • Catestatin regulates vesicular quanta through modulation of cholinergic and peptidergic (PACAPergic) stimulation in PC12 cells
  • Social stress shortens lifespan in mice
  • Stress, overeating, and obesity: Insights from human studies and preclinical models
  • Renal Denervation Normalizes Arterial Pressure with No Effect on Glucose Metabolism or Renal Inflammation in Obese Hypertensive Mice
  • Some dystrophy phenotypes of dystrophin-deficient mdx mice are exacerbated by mild, repetitive daily stress
  • Preliminary Evidence That Resting State Heart Rate Variability Predicts Reactivity to Tactile Stimuli in Rett Syndrome
  • Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis
  • Acute AT 1 R blockade prevents isoproterenol-induced injury in mdx hearts
  • Correction: The molecular identity of the TLQP-21 peptide receptor (Cellular and Molecular Life Sciences, (2021), 78, 23, (7133-7144), 10.1007/s00018-021-03944-1)
  • Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
  • Integrative effects of dystrophin loss on metabolic function of the mdx mouse
  • Clearance kinetics of the VGF-derived neuropeptide TLQP-21
  • Adaptive/innate immunity balance in a complex social world
  • Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38
  • Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis
  • The multiple roles of life stress in metabolic disorders
  • Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21
  • Optogenetic-induced sympathetic neuromodulation of brown adipose tissue thermogenesis
  • High frequency hearing loss and hyperactivity in DUX4 transgenic mice
  • Animal Models Relevant for Geroscience: Current Trends and Future Perspectives in Biomarkers, and Measures of Biological Aging
  • Role of clathrin in dense core vesicle biogenesis
  • Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice
  • The Dichotomous Effect of Chronic Stress on Obesity
  • Juvenile exposure to doxorubicin alters the cardiovascular response to adult-onset psychosocial stress in mice
  • Divergent Cardiac Effects of Angiotensin II and Isoproterenol Following Juvenile Exposure to Doxorubicin
  • b-Adrenergic receptors control brown adipose UCP-1 tone and cold response without affecting its circadian rhythmicity
  • Effect of beta-blocker therapy on weight loss outcomes after sleeve gastrectomy & Roux-en-Y gastric bypass
  • Chronic stress aggravates glucose intolerance in leptin receptor-deficient (db/db) mice
  • Co-administration of resveratrol with doxorubicin in youngmice attenuates detrimental late-occurring cardiovascular changes
  • Social stress is lethal in the mdx model of Duchenne muscular dystrophy
  • Chronic Social and Psychological Stress Impact Select Neuropathologies in the PS19 Mouse Model of Tauopathy
  • Chronic subordination stress phase advances adrenal and anterior pituitary clock gene rhythms
  • Brown adipose tissue involution associated with progressive restriction in progenitor competence
  • Chronic Subordination Stress Induces Hyperphagia and Disrupts Eating Behavior in Mice Modeling Binge-Eating-Like Disorder
  • Identification of new candidate biomarkers to support doxorubicin treatments in canine cancer patients
  • NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health
  • The neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis
  • Stress and Alzheimer's disease: A senescence link?
  • Role of VGF-derived carboxy-terminal peptides in energy balance and reproduction: Analysis of "humanized" knockin mice expressing full-length or truncated VGF
  • VGF-Derived Peptide TLQP-21: Structure, Function, and Biomedical Implications
  • Social stress, immune functions and immuno-endocrine disorders in rodents and other animals
  • From psychosocial stress to herpes simplex infection: A sequence of coordinated events regulated in a cascade fashion
  • Effects of housing social context on emotional behaviour and physiological responses in female mice
  • Pathophysiological role of TLQP-21: Gastrointestinal and metabolic functions
  • Advancements in neuroendocrine and autonomic control of metabolic functions and their pathological significance
  • Resource loss and stress-related disease: Is there a link?
  • Interaction with stressed mothers affects corticosterone levels in pups after reunion and impairs the response to dexamethasone in adult mice
  • Implication of the VGF-derived peptide TLQP-21 in mouse acute and chronic stress responses
  • Stress and depression: Preclinical research and clinical implications
  • Conditional inactivation of neuropeptide y Y1 receptors unravels the role of Y1 and Y5 receptors coexpressing neurons in anxiety
  • Erratum: Chronic psychosocial stress-induced down-regulation of immunity depends upon individual factors (Journal of Neuroimmunology (2003) 141 (58-64) DOI: 10.1016/S0165-5728(03)00220-0)
  • Psychosocial stress affects energy balance in mice: Modulation by social status
  • Chronic psychosocial stress down-regulates central cytokines mRNA
  • Granins and catecholamines. Functional interaction in chromaffin cells and adipose tissue.
  • In judo, Randori (free fight) and Kata (highly ritualized fight) differentially change plasma cortisol, testosterone, and interleukin levels in male participants
  • Personality traits and endocrine response as possible asymmetry factors of agonistic outcome in karate athletes
  • Behavioral and physiological characterization of male mice under chronic psychosocial stress
  • Chronic intracerebroventricular injection of TLQP-21 prevents high fat diet induced weight gain in fast weight-gaining mice
  • Acute and chronic social defeat: Stress protocols and behavioral testing
  • The rank assessed in a food competition test influences subsequent reactivity to immune and social challenges in mice
  • Sildenafil counteracts the inhibitory effect of social subordination on competitive aggression and sexual motivation in male mice
  • The VGF-derived peptide TLQP-21: A new modulatory peptide for inflammatory pain
  • Granins as disease-biomarkers: Translational potential for psychiatric and neurological disorders
  • TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity
  • On-ground housing in "Mice Drawer System" (MDS) cage affects locomotor behaviour but not anxiety in male mice
  • Increased vulnerability to psychosocial stress in heterozygous serotonin transporter knockout mice
  • Stress-induced susceptibility to sudden cardiac death in mice with altered serotonin homeostasis
  • The Obese Species: A special issue on obesity and metabolic disorders
  • Regulatory functions of limbic Y1 receptors in body weight and anxiety uncovered by conditional knockout and maternal care
  • Corrigendum to "Granins as disease-biomarkers: Translational potential for psychiatric and neurological disorders,". [Neuroscience 170/1 (2010) 289-297]
  • Characterization of a novel peripheral pro-lipolytic mechanism in mice: Role of VGF-derived peptide TLQP-21
  • Chronic administration of olanzapine induces metabolic and food intake alterations: A mouse model of the atypical antipsychotic-associated adverse effects
  • Neuropeptide TLQP-21, a VGF internal fragment, modulates hormonal gene expression and secretion in GH3 cell line
  • Stress revisited: A critical evaluation of the stress concept
  • Social factors and individual vulnerability to chronic stress exposure
  • Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice
  • Metabolic consequences and vulnerability to diet-induced obesity in male mice under chronic social stress
  • Psychosocial stress induces hyperphagia and exacerbates diet-induced insulin resistance and the manifestations of the Metabolic Syndrome
  • Cross fostering in mice: Behavioral and physiological carry-over effects in adulthood
  • Social stress, immune functions and disease in rodents
  • Age at group formation alters behavior and physiology in male but not female CD-1 mice
  • The role of the vgf gene and VGF-derived peptides in nutrition and metabolism
  • The extended granin family: Structure, function, and biomedical implications
  • An efficient and reproducible method for transformation of genetically recalcitrant bifidobacteria
  • Effects of chronic psychosocial stress on cardiac autonomic responsiveness and myocardial structure in mice
  • The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure
  • The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanism
  • Loss of Gnas imprinting differentially affects REM/NREM sleep and cognition in mice
  • Chronic intracerebroventricular TLQP-21 delivery does not modulate the GH/IGF-1-axis and muscle strength in mice
  • Selective enhancement of spatial learning under chronic psychosocial stress
  • Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
  • Individual housing induces altered immuno-endocrine responses to psychological stress in male mice
  • Social status in mice: Behavioral, endocrine and immune changes are context dependent
  • Chronic psychosocial stress persistently alters autonomic function and physical activity in mice
  • Group housed mice: Are they really stressed?
  • Chronic psychosocial stress-induced down-regulation of immunity depends upon individual factors
  • Learning to cope with two different food distributions: The performance of house mice (Mus musculus domesticus)
  • How tree shrews (Tupaia belangeri) perform in a searching task: Evidence for strategy use
  • Scarce and unpredictable, yet obesogenic: modeling the impact of food insecurity on adiposity in mice

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Co-workers & collaborators

  • Jan M. van Deursen

  • Jesse W. Williams

  • Laura J. Niedernhofer

  • Darren J. Baker

  • Maria Razzoli

  • Carey E. Lyons

Alessandro Bartolomucci's public data