Flow chart for the four diagnostic approaches, using Centiloid values, summarizing the results in the last column.
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posted on 2024-05-20, 17:32 authored by Hanneke F. M. Rhodius-Meester, Ingrid S. van Maurik, Lyduine E. Collij, Aniek M. van Gils, Juha Koikkalainen, Antti Tolonen, Yolande A. L. Pijnenburg, Johannes Berkhof, Frederik Barkhof, Elsmarieke van de Giessen, Jyrki Lötjönen, Wiesje M. van der FlierAUC: appropriate use criteria, AUC+: patients fulfilling appropriate use criteria according to [13], operationalized as described in [14], PCC: probability of correct class, NP: neuropsychology, MRI: magnetic resonance imaging, Sim: simulate, FU: follow-up.
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limited sensitivity hindersleast one scenariocould support clinicians108 alzheimer ’amsterdam dementia cohort18 10 vascular dementiamemory clinic patientsppc ≥ 0included 286 subjectsappropriate use criteria66 %) patients21 %) patientscomputerized decision support54 %), 2pet 40 %)disease dementiadementia workupbalanced decision[< sup55 %),select patientspatients diagnosedcomputerized dataxlink ">work contributesuncertain classificationthree scenariossufficient certaintysubjects usingpet scanspet accordingoptimal uselimitedly availableguide selectionfirst classifiedfinal classificationenriched classificationeffective implementationdsi classifierdiagnostic classificationcorrect classcomputerized approachclinical utilityclinical practiceassessed whether135 controls
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