12940_2017_267_MOESM4_ESM.pptx (550.76 kB)

Additional file 4: of The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression

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posted on 2017-06-14, 05:00 authored by Emily Winterbottom, Devin Koestler, Dennis Fei, Eric Wika, Anthony Capobianco, Carmen Marsit, Margaret Karagas, David Robbins
Adjustment for AQP9 expression attenuates the associations of a subset of developmental genes with U-As in female fetal placenta. Multivariable linear regression analyses were performed to determine the association of U-As levels with developmental/stemness gene expression in female fetal placenta, (A) without or (B) with adjustment for AQP9 expression. All analyses were adjusted for maternal age. *P < 0.05, **P < 0.01, ***P < 0.001. Green; HH pathway-related genes, purple; NOTCH pathway-related genes, blue; WNT pathway-related genes, orange; stemness genes. (PPTX 550 kb)