Nutrient-dependent / pheromone-controlled adaptive evolution
(a mammalian model of thermodynamics and organism-level thermoregulation)
This model refutes a book-length revision of a theory: ‘Mutation-driven evolution’
CHEMICAL ECOLOGY; SYSTEMS BIOLOGY; ACROSS SPECIES COMPARISONS
Examples of nutrient-dependent amino acid substitutions clarify the involvement of
seemingly futile thermodynamic control of intracellular and intermolecular
interactions, which result in de novo creation of olfactory receptor genes.
Thermodynamically controlled cycles of RNA transcription and protein degradation
are responsible for organism-level changes in pheromone production, which enable
accelerated changes in the miRNA/mRNA balance and thermoregulation of controlled
nutrient-dependent adaptive evolution.