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Ignition and node metastability differences among cisgender and transgender young healthy adults

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posted on 2021-11-18, 21:30 authored by Carme UribeCarme Uribe, Anira Escrichs
The intrinsic-ignition framework was applied to a sample of cisgender and transgender young adults (Deco and Kringelbach 2017, Deco et al., 2017).
Ignition and metastability values from the 17-network Schaefer atlas (Schaefer et al., 2018) can be downloaded as Matlab matrices (.mat).

Legend:
CONT: control executive
DMN: default mode
DORSATT: dorsal attention
SAL: ventral attention/salience
LIM: limbic
MTR: somatomotor
VI: visual

A general linear model and Monte Carlo permutation testing with 1,000 iterations to control type-I errors were applied to perform group comparisons. Age and years of education were included as covariates of no interest in the ciswomen vs transmen contrast, and education for the cismen vs transmen. Non-covariate results are also available.

- Deco, G. and Kringelbach, M. L. (2017). Hierarchy of Information Processing in the Brain: A Novel Intrinsic Ignition Framework. Neuron, 94(5):961–968.
- Deco, G., Tagliazucchi, E., Laufs, H., Sanjuan, A., and Kringelbach, M. L. (2017). Novel intrinsic ignition method measuring local-global integration characterizes wakefulness and deep sleep.eNeuro, 4(5):1–12.
- Schaefer, A., Kong, R., Gordon, E. M., Laumann, T. O., Zuo, X.N., Holmes, A. J., Eickhoff, S.B., and Yeo, B.T.T. (2018). Local-Global Parcellation of the Human Cerebral Cortex from Intrinsic Functional Connectivity MRI. Cerebral Cortex, 28(9):3095–3114.

Funding

Marie Sklodowska-Curie grant agreement 888692

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