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posted on 24.08.2017, 01:52 by Juana Del Valle Mendoza, Wilmer Silva-Caso, Angela Cornejo-Tapia, Fiorella Orellana-Peralta, Eduardo Verne, Claudia Ugarte, Miguel Angel Aguilar-Luis, María del Carmen De Lama-Odria, Ronald Nazario-Fuertes, Mónica Esquivel-Vizcarra, Verónica Casabona-Ore, Pablo Weilg, Luis J. del Valle

Molecular etiological profile of atypical bacterial pathogens, viruses and coinfections among infants and children with community acquired pneumonia admitted to a national hospital in Lima, Peru.

Abstract

Objetive: The main objective of this study was to detect the presence of 14 respiratory viruses and atypical bacteria (Mycoplasma pneumoniae, Chlamydia pneumoniae), via Polymerase Chain Reaction in patients under 18 years old hospitalized due to CAP from Lima, Peru.

Results: Atypical pathogens were detected in 39.73% (58/146); viral etiologies in 35.62% (52/146) and coinfections in 18.49% (27/146). The most common etiological agent was M. pneumoniae (n=47), followed by C. pneumoniae (n=11). The most frequent respiratory viruses detected were: respiratory syncytial virus A (n= 35), influenza virus C (n= 21) and parainfluenza virus (n= 10). Viral-bacterial and bacterium-bacterium coinfections were found in 27 cases. In our study population, atypical bacteria (39.73%) were detected as frequently as respiratory viruses (35.62%). The presence of M. pneumoniae and C. pneumoniae should not be underestimated as they can be commonly isolated in Peruvian children with CAP.

Funding

This work was syupported by grants from Programa de Ciencia y Tecnología (FINCyT- PIN-2008) from the Peru.

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