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Movie S1 - Darinaparsin Is a Multivalent Chemotherapeutic Which Induces Incomplete Stress Response with Disruption of Microtubules and Shh Signaling

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posted on 15.11.2011, 00:25 by Twila A. Mason, Elena Kolobova, Jiang Liu, Joseph T. Roland, Chin Chiang, James R. Goldenring

Stress granules must complete formation before dispersal. HeLa cells were transfected with pcherry-G3BP using Effectene. Cells were treated with 0.05 mM darinaparsin for 30 minutes, washed with serum-free media twice, then incubated in complete media for recovery.